Potential benefits of vitamin D for patients with systemic lupus erythematosus.
Potential benefits of vitamin D for patients with systemic lupus erythematosus.
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DOI：
10.4161/derm.20443
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发表时间：
2012-04-01
期刊：
影响因子：
--
通讯作者：
Kamen DL
中科院分区：
文献类型：
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作者：
Singh A;Kamen DL
Systemic lupus erythematosus (SLE) is a complex multi-system autoimmune disease. Vitamin D deficiency has been proposed as an environmental trigger of disease onset and as a contributor to increased SLE activity. SLE patients are prone to develop vitamin D deficiency because of photosensitivity leading to sun avoidance and other sun protective measures. The impact of vitamin D on immune function previously seen in vitro and in cross-sectional studies has now been shown in prospective human studies, strengthening the evidence that there is a connection between SLE and vitamin D status. This review describes the role of vitamin D on immune function, prevalence of vitamin D deficiency in patients with SLE, identify risk factors for deficiency, describe the consequences of deficiency in SLE patients, and review current vitamin D recommendations for patients with SLE.
