Functional Characterization of the Human Speech Articulation Network
Functional Characterization of the Human Speech Articulation Network
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DOI：
10.1093/cercor/bhx100
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发表时间：
2018-05-01
期刊：
影响因子：
3.7
通讯作者：
Fedorenko, Evelina
中科院分区：
文献类型：
--
作者：
Basilakos, Alexandra;Smith, Kimberly G.;Fedorenko, Evelina
许多大脑区域都与发音有关，但它们的精确计算仍然存在争议。使用功能性磁共振成像，我们检查了发音反应脑区域的功能特异性程度，以限制有关其对语言产生贡献的假设。我们发现发音响应区域(1)对发音复杂性敏感，但(2)与附近支持多种目标导向行为的域一般区域在很大程度上不重叠。此外，运动前发音区域对某些相关任务（呼吸控制）的语音产生表现出选择性，但对其他任务（非言语口腔运动[NSO]运动）则没有选择性。言语和非言语运动之间的重叠与皮质电图证据一致，这些区域编码发音器及其状态，也与患者证据一致，发音缺陷通常伴随着口腔运动缺陷。相比之下，颞上区对发音表现出较强的选择性，这表明这些区域在言语计划/产生中起着特定的作用。最后，后额下回的发音反应部分对发音表现出一定的选择性，这与该区域准备传递给运动前皮层的发音代码的假设一致。综上所述，这些结果为人类发音系统的结构提供了信息。
A number of brain regions have been implicated in articulation, but their precise computations remain debated. Using functional magnetic resonance imaging, we examine the degree of functional specificity of articulation-responsive brain regions to constrain hypotheses about their contributions to speech production. We find that articulation-responsive regions (1) are sensitive to articulatory complexity, but (2) are largely nonoverlapping with nearby domain-general regions that support diverse goal-directed behaviors. Furthermore, premotor articulation regions show selectivity for speech production over some related tasks (respiration control), but not others (nonspeech oral-motor [NSO] movements). This overlap between speech and nonspeech movements concords with electrocorticographic evidence that these regions encode articulators and their states, and with patient evidence whereby articulatory deficits are often accompanied by oral-motor deficits. In contrast, the superior temporal regions show strong selectivity for articulation relative to nonspeech movements, suggesting that these regions play a specific role in speech planning/production. Finally, articulation-responsive portions of posterior inferior frontal gyrus show some selectivity for articulation, in line with the hypothesis that this region prepares an articulatory code that is passed to the premotor cortex. Taken together, these results inform the architecture of the human articulation system.