Beware the pitfalls of beauty : High-quality myocardial images with resolution recovery.
Beware the pitfalls of beauty : High-quality myocardial images with resolution recovery.
复制标题
谨防美丽的陷阱：分辨率恢复的高质量心肌图像。
DOI：
10.1007/s12350-019-01715-x
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发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Piotr Slomka
中科院分区：
文献类型：
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作者：
Kenichi Nakajima;Hiroto Yoneyama;Piotr Slomka
心肌单光子发射计算机断层扫描（SPECT）通常被认为是一种低分辨率的成像方式，并且考虑到灌注是核心脏病学的主要评估，在多模态心脏成像时代，不完美的SPECT图像可能是可以接受的。虽然我们考虑到这些因素来考虑此类核图像的质量，但我们最初对使用碲化镉锌（CZT）相机（例如D-SPECT 1）创建的心肌灌注图像印象深刻，因为图像质量在视觉上与正电子发射计算机断层扫描（PET）生成的图像质量相当。使用旋转Anger相机采集的常规SPECT图像在临床条件下的平均分辨率为15 mm，2因此质量低于使用磁共振成像和X射线计算机断层扫描采集的高分辨率图像。当使用具有专用准直器和重建方法的CZT相机获得图像时，图像质量变得更加精细，并且可以清楚地可视化薄的心肌壁。此外，新相机适用于肥胖患者，注射示踪剂的剂量较低，可以快速获取图像，并且可以在常规临床研究中进行动态获取。3-6在大多数临床条件下，使用具有专用准直器和专有迭代重建的CZT相机获得的数据，包括空间分辨率中准直器相关损失的分辨率恢复，还可以包括心脏解剖模型（心脏先验），其约束频谱动力学（SD）的左心室壁3的形状和厚度（以色列塞萨里亚）的相机似乎工作良好，提供高分辨率的数据采集和处理。由于超声心动图上的心肌厚度范围从几mm到10 mm，因此在核成像中需要使用适当的模型重建薄壁的方法。即使使用门控SPECT成像，虽然心脏和呼吸运动是一个尚待解决的重要问题，但在多模式心脏成像时代，更高的分辨率更可取。
Myocardial single-photon emission computed tomography (SPECT) is generally recognized as a lowresolution imaging modality, and given that perfusion is a primary assessment by nuclear cardiology, imperfect SPECT images might be acceptable in the era of multimodal cardiac imaging. While we considered the quality of such nuclear images with these factors in mind, we were initially impressed by myocardial perfusion images created using cadmium-zinc telluride (CZT) cameras such as D-SPECT 1 because the image quality was visually comparable to that generated by positron emission computed tomography (PET). Conventional SPECT images acquired using rotating Anger cameras have an average resolution of 15 mm under clinical conditions, 2 and thus the quality is inferior to that highresolution images acquired using magnetic resonance imaging and X-ray computed tomography. The quality of images has become more refined when obtained with CZT cameras with dedicated collimators and reconstruction methods, and thin myocardial walls can be clearly visualized. In addition, new cameras are suitable for obese patients, the dose of injected tracers is lower, images can be rapidly acquired, and dynamic acquisitions are possible in routine clinical investigations. 3-6Under most clinical conditions, data obtained with the CZT cameras with dedicated collimators and proprietary iterative reconstruction, which includes resolution recovery for the collimator-related loss in spatial resolution and also can include the cardiac anatomic model (heart prior), which constrains the shape and thickness of left ventricular walls 3 for Spectrum Dynamics (SD)(Cesarea, Israel) cameras, seems to work well, providing high-resolution data acquisition and processing. Since myocardial thickness ranges from a few to 10 mm on echocardiograms, a method of reconstructing thin walls using appropriate models is desirable in nuclear imaging. Even with gated SPECT imaging, while cardiac and respiratory motion is an important issue that remains to be resolved, higher resolution is preferable in the era of multi-modal cardiac imaging.