Carbon “quantum” dots for bioapplications
Carbon “quantum” dots for bioapplications
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DOI：
10.1177/15353702211057513
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发表时间：
2021-12
影响因子：
3.2
通讯作者：
Dekai Yuan;Ping Wang;Liju Yang;Jesse L Quimby;Ya‐Ping Sun
中科院分区：
文献类型：
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作者：
Dekai Yuan;Ping Wang;Liju Yang;Jesse L Quimby;Ya‐Ping Sun
碳“量子”点或碳量子点（CDot）利用和增强小碳纳米颗粒的固有光激发态性质和过程，经由通过有机物质的化学官能化的有效纳米颗粒表面钝化。CDots的光学性质和光致氧化还原特性与已建立的常规半导体量子点以及富勒烯和其他碳纳米材料的光学性质和光致氧化还原特性具有竞争力。这里强调的是在探索CDots的主要进展，因为它们作为高性能但无毒的荧光探针，用于体外和体内的单光子和多光子生物成像，以及它们独特的强效抗菌功能，在可见光/自然光或环境光条件下有效地和高效地杀灭一些最棘手的细菌病原体和病毒。讨论了CDots平台和相关技术进一步发展的机遇和挑战。
Carbon “quantum” dots or carbon dots (CDots) exploit and enhance the intrinsic photoexcited state properties and processes of small carbon nanoparticles via effective nanoparticle surface passivation by chemical functionalization with organic species. The optical properties and photoinduced redox characteristics of CDots are competitive to those of established conventional semiconductor quantum dots and also fullerenes and other carbon nanomaterials. Highlighted here are major advances in the exploration of CDots for their serving as high-performance yet nontoxic fluorescence probes for one- and multi-photon bioimaging in vitro and in vivo, and for their uniquely potent antimicrobial function to inactivate effectively and efficiently some of the toughest bacterial pathogens and viruses under visible/natural or ambient light conditions. Opportunities and challenges in the further development of the CDots platform and related technologies are discussed.