Converging evidence for a cognitive anomaly in early psychopathology
Converging evidence for a cognitive anomaly in early psychopathology
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DOI:
10.1017/s0048577299951727
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发表时间:
1999-07-01
期刊:
影响因子:
3.7
通讯作者:
Miller, GA
中科院分区:
文献类型:
--
作者:
Fernandes, LOL;Keller, J;Miller, GA
Subcomponents of the N200 component of the event-related brain potential believed to be differentially sensitive to involuntary and voluntary cognitive processes were examined. Nonpatients (N = 131) identified initially by the Chapman and Depue research scales and classified later on the basis of diagnostic symptom clusters and family psychiatric history provided converging evidence for an intact mismatch negativity subcomponent. In contrast, the N2b subcomponent distinguished several groups of subjects. Results suggested abnormal voluntary cognitive processing, perhaps reflecting compensatory efforts in subjects at risk for or manifesting psychopathology, particularly those showing negative symptoms.