Evaluating serum alpha-tocopherol (vitamin E) in terms of a lipid ratio.
Evaluating serum alpha-tocopherol (vitamin E) in terms of a lipid ratio.
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根据脂质比率评估血清 α-生育酚（维生素 E）。
DOI：
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发表时间：
1999
影响因子：
0.8
通讯作者：
KL Nuttall
中科院分区：
文献类型：
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作者：
Andrea N. Winbauer;SS Pingree;KL Nuttall
众所周知，准确评估血清α-生育酚需要了解同时存在的血清脂质。使用5-18 mg/L标准参考限内的患者样本（n = 307）来确定以下α-生育酚与胆固醇和甘油三酯总和的脂质比的95%参考区间[E/（C + T）]：1.4（1.20-1.56）- 5.7（5.51-6.91）mg/g（90%置信区间）。在α-生育酚状态方面，低结果（< 5 mg/L）的患者在重新评估时正常，47%的受检者（59人中的28人）的脂质比率正常，58%的患者（4.5人中的26人）的结果升高（> 18 mg/L）正常或低。当不考虑血脂时，非空腹标本中甘油三酯升高是误导结果的一个常见原因。当测量患者人群中的α-生育酚时，需要评价脂质含量，以便在大量病例中进行准确评估。
It is well known that accurate assessment of serum alpha-tocopherol requires knowledge of the serum lipids also present. Patient specimens (n = 307) within the standard reference limit of 5-18 mg/L were used to determine the following 95 percent reference interval for a lipid ratio of alpha-tocopherol to the sum of cholesterol and triglycerides [E/(C + T)]: 1.4 (1.20-1.56) - 5.7 (5.51-6.91) mg/g (90 percent confidence interval). In terms of alpha-tocopherol status, patients with low results (< 5 mg/L) were normal on reevaluation with the lipid ratio in 47 percent of those examined (28 of 59), and elevated results (> 18 mg/L) were normal or low in 58 percent (26 of 4.5). Elevated triglycerides developed from non-fasting specimens were one common reason for misleading results when lipids were not considered. When measuring alpha-tocopherol in a patient population, evaluation of the lipid content is needed for accurate assessment in a significant number of cases.