Dye–collagen interactions. Mechanism, kinetic and thermodynamic analysis
Dye–collagen interactions. Mechanism, kinetic and thermodynamic analysis
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DOI：
10.1039/c5ra08611f
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发表时间：
2015-06
期刊：
影响因子：
3.9
通讯作者：
Maria V. Tuttolomondo;J. Galdopórpora;Léa Trichet;H. Voisin;T. Coradin;M. Desimone
中科院分区：
文献类型：
--
作者：
Maria V. Tuttolomondo;J. Galdopórpora;Léa Trichet;H. Voisin;T. Coradin;M. Desimone
一大类偶氮染料已被开发并用于纺织工业，包括皮革染色，因此有望与胶原基材料表现出强烈的相互作用。本文研究了雷马唑黑B染料在I型胶原水凝胶上的吸附机理。在碱性条件下，染料的保留率更高、更强，这与水凝胶的热稳定性和机械稳定性增强有关。通过对吸附反应的动力学和热力学的详细分析，提出并支持了通过Michael反应在染料和蛋白质网络之间形成共价键。ⅰ型胶原蛋白水凝胶具有成本低、吸附快、负载高、保留能力强、储存体积小等特点，是染料修复的理想材料。染料改性水凝胶也可以在生物医学领域找到应用。
A large family of azo dyes have been developed and used in the textile industry, including for leather tainting, and are therefore expected to exhibit strong interactions with collagen-based materials. Here we investigate the mechanisms of adsorption of the Remazol black B dye on type I collagen hydrogel. Higher and stronger retention of the dye is achieved in alkaline conditions, correlated with enhanced thermal and mechanical stability of the hydrogel. The formation of a covalent bond between the dye and the protein network via a Michael reaction is suggested and supported by the detailed analysis of the kinetics and thermodynamics of the sorption reaction. Type I collagen hydrogels combine low cost, fast sorption, high loading and strong retention capacity together with low storage volume, making them promising materials for dye remediation. Dye-modified hydrogels may also find applications in the biomedical field.