A new model for calculating auditory excitation patterns and loudness for cases of cochlear hearing loss

A new model for calculating auditory excitation patterns and loudness for cases of cochlear hearing loss
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用于计算耳蜗听力损失病例的听觉激励模式和响度的新模型

DOI:
10.1016/j.heares.2011.09.007
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发表时间:
2011-12-01
期刊:
影响因子:
2.8
通讯作者:
Moore, Brian C. J.
Moore, Brian C. J.
中科院分区:
医学1区
文献类型:
--
作者:
Chen, Zhangli;Hu, Guangshu;Moore, Brian C. J.

文献摘要

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将计算正常听力稳定声音的听觉激励模式和响度的模型扩展到处理耳蜗听力损失。模型中使用的滤波器具有双roex形状,窄有源滤波器的增益由宽无源滤波器的输出控制。假设每个听力频率下的听力损失可分为外毛细胞(OHCs)功能障碍引起的听力损失和内毛细胞(ihc)功能障碍引起的听力损失。通过降低有源滤波器的最大增益来模拟热盐损耗,这导致绝对阈值增加,压缩非线性降低,频率选择性降低。IHC损失是通过电平依赖的激发电平衰减来模拟的,这导致绝对阈值升高。OHC损失和IHC损失的大小可以通过测量响度增加和测量的绝对阈值,使用迭代程序得出。该模型准确拟合单侧或高度不对称耳蜗听力损失受试者获得的响度招募数据,这些受试者需要在交替呈现给两耳的音调之间进行响度匹配。在相同的参数下,该模型较好地预测了窄带和宽带声音的响度匹配,反映了响度总和。该模型还可以预测何时存在死区。(C) 2011 Elsevier B.V.版权所有
A model for calculating auditory excitation patterns and loudness for steady sounds for normal hearing is extended to deal with cochlear hearing loss. The filters used in the model have a double ROEX-shape, the gain of the narrow active filter being controlled by the output of the broad passive filter. It is assumed that the hearing loss at each audiometric frequency can be partitioned into a loss due to dysfunction of outer hair cells (OHCs) and a loss due to dysfunction of inner hair cells (IHCs). OHC loss is modeled by decreasing the maximum gain of the active filter, which results in increased absolute threshold, reduced compressive nonlinearity and reduced frequency selectivity. IHC loss is modeled by a level-dependent attenuation of excitation level, which results in elevated absolute threshold. The magnitude of OHC loss and IHC loss can be derived from measures of loudness recruitment and the measured absolute threshold, using an iterative procedure. The model accurately fits loudness recruitment data obtained using subjects with unilateral or highly asymmetric cochlear hearing loss who were required to make loudness matches between tones presented alternately to the two ears. With the same parameters, the model predicted loudness matches between narrowband and broadband sound reasonably well, reflecting loudness summation. The model can also predict when a dead region is present. (C) 2011 Elsevier B.V. All rights reserved.