The Terminal Portion of the T Wave: A New Electrocardiographic Marker of Risk of Ventricular Arrhythmias
The Terminal Portion of the T Wave: A New Electrocardiographic Marker of Risk of Ventricular Arrhythmias
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T 波的终末部分：室性心律失常风险的新心电图标记
DOI：
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发表时间：
2000
期刊：
影响因子：
--
通讯作者：
G. Świątecka
中科院分区：
文献类型：
--
作者：
A. Lubiński;Z. Kornacewicz‐Jach;Wnuk;J. Adamus;M. Kempa;T. Królak;E. Lewicka;M. Radomski;G. Świątecka
实验研究表明，跨室壁复极离散度(DOR)，即心肌中M细胞、心外膜细胞和心内膜细胞之间动作电位时程的差异，反映在体表心电图T波终末部分(TpTe)的时程中。由于DOR是与折返性心律失常倾向相关的重要因素，本研究探讨了TpTe是否可作为室性心律失常风险的标志物。对18例冠心病伴诱发性室性心动过速患者(VT组)和16例无诱发性VT的心肌梗塞存活者(对照组)的资料进行比较。在每一次24小时心电记录中自动测量TpTe，并在抗心律失常非药物状态下进行程序化的心室刺激。TpTe以毫秒为单位表示绝对间期，与QTE持续时间(TpTe/QTe×100%)相关。室性心动过速组TpTe时限为74±14ms，对照组为63±16ms(P<；0.004)。室上性心动过速组TpTe间期占QT间期的百分比为21±4%，对照组为17±3%(P=0.02)。在冠心病患者中，有诱导性室性心动过速患者的TpTe较无诱发性室速患者的TpTe延长。本研究结果支持TpTe反映跨室壁复极离散度的假设。
Experimental studies have shown that transmural dispersion of repolarization (DoR), defined as the difference in action potential duration between mid‐myocardial M‐cells, epicardial, and endocardial cells is reflected in the duration of the terminal portion of the T wave (TpTe) on the surface ECG. Since DoR is an important factor associated with the propensity for reentrant arrhythmias, this study examined if TpTe may serve as a marker of risk of ventricular arrhythmias. Data from 18 patients with coronary artery disease and inducible sustained ventricular tachycardia (VT group) were compared with those of 16 survivors of myocardial infarction without inducible VT (control group). TpTe was automatically measured in each beat of 24‐hour ECG recordings, and programmed ventricular stimulation was performed in the antiarrhythmic drug‐free state. TpTe was expressed as the absolute interval in milliseconds, and relative to the duration of QTe (TpTe/QTe × 100%). TpTe duration was 74 ± 14 ms in the VT group versus 63 ± 16 ms in the control group (P < 0.004). The TpTe interval expressed as a percent of the QT interval was 21 ± 4% in the VT group versus 17 ± 3% in the control group (P = 0.02). In patients with coronary artery disease, TpTe was longer in patients with, versus without, inducible VT. The results of this study support the hypothesis that TpTe reflects transmural dispersion of repolarization.
影响因子：
158.5
作者：
ROSENBAUM, DS;JACKSON, LE;COHEN, RJ
通讯作者：
COHEN, RJ
DOI：
10.1016/s0735-1097(96)00377-4
发表时间：
1996-12-01
影响因子：
24
作者：
Antzelevitch, C;Sun, ZQ;Yan, GX
通讯作者：
Yan, GX
影响因子：
20.1
作者：
SICOURI, S;ANTZELEVITCH, C
通讯作者：
ANTZELEVITCH, C