A mitogen-activated protein kinase phosphatase influences grain size and weight in rice.
A mitogen-activated protein kinase phosphatase influences grain size and weight in rice.
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丝裂原激活的蛋白激酶磷酸酶影响水稻的籽粒大小和重量。
DOI：
10.1111/tpj.13971
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发表时间：
2018
期刊：
影响因子：
7.2
通讯作者：
Li Yunhai
中科院分区：
文献类型：
--
作者：
Xu Ran;Yu Haiyue;Wang Junmin;Duan Penggen;Zhang Baolan;Li Jing;Li Yu;Xu Jinsong;Lyu Jia;Li Na;Chai Tuanyao;Li Yunhai
粮食的大小和重量与粮食产量直接相关。然而，决定最终晶粒大小和重量的分子机制在很大程度上仍然未知。在这里，我们描述了两个大晶粒突变体，大晶粒8‐1（large8‐1）和大晶粒8‐2（large8‐2）。large8编码有丝分裂原活化蛋白激酶磷酸酶1 （OsMKP1）。功能突变inosmkp1缺失导致晶粒大，而过表达osmkp1导致晶粒小。OsMKP1通过限制谷壳细胞增殖来决定谷粒大小。OsMKP1直接与有丝分裂原激活蛋白激酶6 （OsMAPK6）相互作用并使其失活。综上所述，我们发现OsMKP1是通过使OsMAPK6失活而影响水稻晶粒大小的关键因素，这表明OsMAPK6的可逆磷酸化在水稻晶粒大小的决定中起着重要作用。
Grain size and weight are directly associated with grain yield in crops. However, the molecular mechanisms that set final grain size and weight remain largely unknown. Here, we characterize two large grain mutants,large grain8‐1(large8‐1) andlarge grain8‐2(large8‐2).LARGE8encodes the mitogen‐activated protein kinase phosphatase1 (OsMKP1). Loss of function mutations inOsMKP1results in large grains, while overexpression ofOsMKP1leads to small grains. OsMKP1 determines grain size by restricting cell proliferation in grain hulls. OsMKP1 directly interacts with and deactivates the mitogen‐activated protein kinase 6 (OsMAPK6). Taken together, we identify OsMKP1 as a crucial factor that influences grain size by deactivating OsMAPK6, indicating that the reversible phosphorylation of OsMAPK6 plays important roles in determining grain size in rice.