On-eye performance of custom wavefront-guided soft contact lenses in a habitual soft lens-wearing keratoconic patient.
On-eye performance of custom wavefront-guided soft contact lenses in a habitual soft lens-wearing keratoconic patient.
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DOI：
10.3928/1081-597x-20071101-18
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发表时间：
2007-11
影响因子：
2.4
通讯作者：
J. Marsack;Katrina E. Parker;Y. Niu;K. Pesudovs;R. Applegate
中科院分区：
文献类型：
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作者：
J. Marsack;Katrina E. Parker;Y. Niu;K. Pesudovs;R. Applegate
目的 评估为一只习惯佩戴软镜片的中度圆锥角膜眼睛生产的波前引导软隐形眼镜的视觉、光学和验配特性。方法 开发了一种生产和评估定制波前引导软隐形眼镜的工艺。使用 COAS-HD 波前传感器（Wavefront Sciences）量化波前像差；包含高阶像差和低阶像差的软性隐形眼镜是使用定制软件设计的，并使用眼科镜片车床生产。将镜片置于人工 5 毫米瞳孔上记录明视高对比度和低对比度 logMAR 视力，并在 5 毫米瞳孔上分析残余的 2 阶至 10 阶均方根 (RMS) 像差。使用 t 检验与眼睛习惯性的复曲面软隐形眼镜进行比较。结果 5 毫米瞳孔的习惯性隐形眼镜和最终定制隐形眼镜的明视高对比度值分别为 0.07+/-0.06 和 -0.08+/-0.05。明视低对比度值分别为0.73+/-0.06和0.62+/-0.07。 5 毫米瞳孔上的习惯性和最终定制校正低阶 RMS 水平分别为 2.08 和 0.34 微米，高阶 RMS 水平分别为 0.77 和 0.39 微米。结论 与习惯性矫正相比，最终的定制隐形眼镜在 5 毫米瞳孔中，明视高对比度 (P=.03) 改善了 1.5 行，明视低对比度 (P=.11) 改善了 1 行。 5 毫米瞳孔的低阶像差和高阶像差分别减少了 84% 和 50%。通过进一步的波前迭代可以实现定制镜片性能的进一步改进。
PURPOSE To assess visual, optical, and fitting characteristics for wavefront-guided soft contact lenses produced for one habitual soft lens-wearing moderate keratoconic eye. METHODS A process for production and evaluation of custom wavefront-guided soft contact lenses was developed. Wavefront aberrations were quantified with the COAS-HD wavefront sensor (Wavefront Sciences); soft contact lenses containing both high and low order aberrations were designed with custom software and produced using an ophthalmic lens lathe. Photopic high and low contrast logMAR visual acuity were recorded with the lens in place over an artificial 5-mm pupil and residual 2nd to 10th order root-mean-square (RMS) aberrations were analyzed over a 5-mm pupil. Comparisons were made to the eye's habitual toric soft contact lens using t tests. RESULTS Photopic high contrast values for habitual and final custom contact lenses for a 5-mm pupil were 0.07+/-0.06 and -0.08+/-0.05, respectively. Photopic low contrast values were 0.73+/-0.06 and 0.62+/-0.07, respectively. Habitual and final custom correction low order RMS over a 5-mm pupil were 2.08 and 0.34 microm, and high order RMS levels were 0.77 and 0.39 microm, respectively. CONCLUSIONS The final custom contact lens showed 1.5 lines of improvement for photopic high contrast (P=.03) and 1 line for photopic low contrast (P=.11) over a 5-mm pupil compared to habitual correction. Low and high order aberrations were reduced by 84% and 50% over a 5-mm pupil, respectively. Further improvements in performance of custom lenses may be achieved with further wavefront iterations.