Test-retest reliability in fMRI of language: Group and task effects
Test-retest reliability in fMRI of language: Group and task effects
复制标题
DOI：
10.1016/j.bandl.2006.04.015
复制
发表时间：
2007-08-01
影响因子：
2.5
通讯作者：
Small, Steven L.
中科院分区：
文献类型：
--
作者：
Chen, E. Elinor;Small, Steven L.
本文探讨了不同被试群体和不同实验任务对重测信度的影响。一组12名健康参与者和一组9名中风患者在不同的日子进行了两次相同的语言成像实验，测试和重新测试。实验包括四个条件，一个音频条件和三个视听条件，其中手是休息，打手势，或执行自适应运动。使用多元线性回归分析成像数据，并将结果进一步用于生成每个个体受试者每种条件的受试者工作特征（ROC）曲线。通过使用曲线下面积作为比较指标，我们发现中风患者在时间上的可靠性低于健康参与者，并且当参与者在讲话时做手势时，他们的成像数据比他们进行与讲话无关的手部运动时更可靠。此外，受试者间的变异性是在手势任务比在任何其他三个条件下的健康参与者，但不是中风患者。(c)2007年由Elsevier Inc.出版
This paper explores how the test-retest reliability is modulated by different groups of participants and experimental tasks. A group of 12 healthy participants and a group of nine stroke patients performed the same language imaging experiment twice, test and retest, on different days. The experiment consists of four conditions, one audio condition and three audiovisual conditions in which the hands are either resting, gesturing, or performing self-adaptive movements. Imaging data were analyzed using multiple linear regression and the results were further used to generate receiver operating characteristic (ROC) curves for each condition for each individual subject. By using area under the curve as a comparison index, we found that stroke patients have less reliability across time than healthy participants, and that when the participants gesture during speech, their imaging data are more reliable than when they are performing hand movements that are not speech-associated. Furthermore, inter-subject variability is less in the gesture task than in any of the other three conditions for healthy participants, but not for stroke patients. (c) 2007 Published by Elsevier Inc.