Clinical Carbapenem-Resistant Acinetobacter baylyi Strain Coharboring blaSIM-1 and blaOXA-23 from China
Clinical Carbapenem-Resistant Acinetobacter baylyi Strain Coharboring blaSIM-1 and blaOXA-23 from China
复制标题
DOI：
10.1128/aac.00425-11
复制
发表时间：
2011-08
影响因子：
4.9
通讯作者：
Zhi-hui Zhou;Xiaoxing Du;Li Wang;Qing Yang;Yi-qi Fu;Yunsong Yu
中科院分区：
文献类型：
--
作者：
Zhi-hui Zhou;Xiaoxing Du;Li Wang;Qing Yang;Yi-qi Fu;Yunsong Yu
在临床碳青霉烯类耐药的贝氏不动杆菌NB 09 A30中共检测到blaSIM-1和blaOXA-23。这两个碳青霉烯酶基因都位于一个大质粒上（ca. 360 kb）。blaSIM-1被发现为插入到1类整合子中的基因盒，与在来自韩国的不动杆菌属分离株中确定的整合子相同。NB 09 A30的blaOXA-23基因结构与来自同一医院的鲍曼不动杆菌CC 92（Acinetobacter baumannii）的基因结构不同。
ABSTRACT blaSIM-1 and blaOXA-23 were codetected in clinical carbapenem-resistant Acinetobacter baylyi strain NB09A30. Both of carbapenemase genes were located on a large plasmid (ca. 360 kb). blaSIM-1 was found as a gene cassette inserted into a class 1 integron identical to that determined in Acinetobacter sp. isolates from South Korea. The genetic structure of blaOXA-23 in NB09A30 was different from that in the prevalent Acinetobacter baumannii of clonal complex 92 (CC92) from the same hospital.