Change of skeletal muscle mass in patients with pheochromocytoma
Change of skeletal muscle mass in patients with pheochromocytoma
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DOI：
10.1007/s00774-018-0959-3
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发表时间：
2019-07-01
影响因子：
3.3
通讯作者：
Kim, Beom-Jun
中科院分区：
文献类型：
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作者：
Lee, Seung Hun;Kwak, Mi Kyung;Kim, Beom-Jun
由于嗜铬细胞瘤引起的儿茶酚胺过量对身体成分（包括骨骼肌质量）的影响尚不清楚。在这里，我们研究了儿茶酚胺代谢产物对嗜铬细胞瘤患者身体成分的影响。采用生物电阻抗法测定16例嗜铬细胞瘤和224例无功能肾上腺意外瘤（NFAI）患者的体成分、尿代谢产物（UM）和尿正代谢产物（UNM），比较两组患者的骨骼肌质量和脂肪质量。校正混杂因素后，UM（=-0.171，P=0.006）和UNM（=-0.249，P
The effects of catecholamine excess due to pheochromocytoma on body composition, including skeletal muscle mass, are unknown. Here, we investigated the effects of catecholamine metabolites on body composition in subjects with pheochromocytoma. After body compositions using bioelectrical impedance analysis, urinary metanephrine (UM), and urinary normetanephrine (UNM) were measured in 16 patients with pheochromocytoma and 224 patients with nonfunctioning adrenal incidentaloma (NFAI), we compared skeletal muscle mass and fat mass (FM) between the two groups. After adjustments for confounders, UM (=-0.171, P=0.006) and UNM (=-0.249, P