Low-motion fMRI data can be obtained in pediatric participants undergoing a 60-minute scan protocol.
Low-motion fMRI data can be obtained in pediatric participants undergoing a 60-minute scan protocol.
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DOI:
10.1038/s41598-020-78885-z
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发表时间:
2020-12-14
影响因子:
4.6
通讯作者:
Constable RT
中科院分区:
文献类型:
--
作者:
Horien C;Fontenelle S 4th;Joseph K;Powell N;Nutor C;Fortes D;Butler M;Powell K;Macris D;Lee K;Greene AS;McPartland JC;Volkmar FR;Scheinost D;Chawarska K;Constable RT
Performing functional magnetic resonance imaging (fMRI) scans of children can be a difficult task, as participants tend to move while being scanned. Head motion represents a significant confound in fMRI connectivity analyses. One approach to limit motion has been to use shorter MRI protocols, though this reduces the reliability of results. Hence, there is a need to implement methods to achieve high-quality, low-motion data while not sacrificing data quantity. Here we show that by using a mock scan protocol prior to a scan, in conjunction with other in-scan steps (weighted blanket and incentive system), it is possible to achieve low-motion fMRI data in pediatric participants (age range: 7–17 years old) undergoing a 60 min MRI session. We also observe that motion is low during the MRI protocol in a separate replication group of participants, including some with autism spectrum disorder. Collectively, the results indicate it is possible to conduct long scan protocols in difficult-to-scan populations and still achieve high-quality data, thus potentially allowing more reliable fMRI findings.
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影响因子:
3.6
作者:
de Bie, Henrica M. A.;Boersma, Maria;Wattjes, Mike P.;Adriaanse, Sofie;Vermeulen, R. Jeroen;Oostrom, Kim J.;Huisman, Jaap;Veltman, Dick J.;Delemarre-Van de Waal, Henriette A.
通讯作者:
Delemarre-Van de Waal, Henriette A.
影响因子:
5.7
作者:
Dosenbach NUF;Koller JM;Earl EA;Miranda-Dominguez O;Klein RL;Van AN;Snyder AZ;Nagel BJ;Nigg JT;Nguyen AL;Wesevich V;Greene DJ;Fair DA
通讯作者:
Fair DA
影响因子:
3.7
作者:
Jolles, Dietsje D.;van Buchem, Mark A.;Rombouts, Serge A. R. B.
通讯作者:
Rombouts, Serge A. R. B.
影响因子:
4.8
作者:
Mueller S;Wang D;Fox MD;Pan R;Lu J;Li K;Sun W;Buckner RL;Liu H
通讯作者:
Liu H
DOI:
10.1111/j.2517-6161.1995.tb02031.x
发表时间:
1995-01-01
影响因子:
5.8
作者:
BENJAMINI, Y;HOCHBERG, Y
通讯作者:
HOCHBERG, Y