Scanning laser polarimetry with variable corneal compensation and optical coherence tomography in tilted disk
Scanning laser polarimetry with variable corneal compensation and optical coherence tomography in tilted disk
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DOI：
10.1016/j.ajo.2006.04.053
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发表时间：
2006-09-01
影响因子：
4.2
通讯作者：
Yoshimura, Nagahisa
中科院分区：
文献类型：
--
作者：
Yu, Saiyuu;Tanabe, Teruyo;Yoshimura, Nagahisa
目得：为了确定是否扫描激光偏振仪与可变角膜补偿（GDx-VCC）或光学相干断层扫描（OCT）是有助于分析的视网膜神经纤维层（RNFL）的厚度在青光眼患者倾斜disk.DESIGN：回顾性病例对照研究。GDx-VCC和OCT测量视盘周围RNFL厚度，Humphrey Field Analyzer program 30-2（HFA）视野测试均在所有受试者中进行。结果：在无倾斜视盘组中，GDx-VCC和OCT分析获得的RNFL厚度值与平均偏差（MD）具有良好的相关性，并清楚地显示出阶段依赖性降低。相反，在椎间盘倾斜组中，GDx-VCC和OCT之间的RNFL测量值存在差异。在每个半视野（上级和下级）进一步检查RNFL测量与视野的相关性。在没有倾斜盘的组中，两种仪器在每个半野的测量值与平均模式偏差值具有良好的相关性。然而，在倾斜盘组中，GDx-VCC导出值与两个半视野中的视野缺损不相关，而OCT与两个平均模式偏差值良好相关。近780 nm的波长采集的红外图像显示从巩膜在倾斜disk.CONCLUSIONS高反射：我们的研究表明，RNFL分析OCT是更适合于青光眼的评估相比，GDx-NCC倾斜盘。
PURPOSE: To determine whether scanning laser polarimetry with variable corneal compensation (GDx-VCC) or optical coherence tomography (OCT) is helpful for the analysis of the retinal nerve fiber layer (RNFL) thickness in glaucoma subjects with tilted disk.DESIGN: Retrospective case-control study.METHODS: We included 21 glaucomatous eyes with tilted disk and 35 glaucomatous eyes without tilted disk. Peripapillary RNFL thickness measurement by GDx-VCC and OCT, and also visual field testing with a Humphrey Field Analyzer program 30-2 (HFA) were performed in all subjects.RESULTS: In the group without tilted disk, the RNFL thickness values obtained with GDx-VCC and OCT analysis had a good correlation with mean deviation (MD), and clearly showed stage-dependent reduction. Conversely, in the group with tilted disk, a discrepancy in the RNFL measurement between GDx-VCC and OCT was ob, served. The correlation of RNFL measurement to the visual field was further examined at each hemifield (superior and inferior). In the group without tilted disk, the measurements of both instruments at each hemifield were in good correlation with the mean pattern deviation values. However, in the group with tilted disk, the GDx-VCC derived values did not correlate with the visual field defect in both hemifields, whereas OCT was in good association with both mean pattern deviation values. Infrared images acquired with a wavelength of nearly 780 nm revealed a high reflex from the sclera in the tilted disk.CONCLUSIONS: Our study has suggested that RNFL analysis by OCT is more suitable for the glaucoma assessment in the tilted disk compared with GDx-NCC.