A 2-pyrone cycloaddition route to functionalised aromatic boronic esters

A 2-pyrone cycloaddition route to functionalised aromatic boronic esters
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DOI:
10.1016/j.tet.2007.08.118
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发表时间:
2008-01-28
期刊:
影响因子:
2.1
通讯作者:
Harrity, Joseph P. A.
Harrity, Joseph P. A.
中科院分区:
化学3区
文献类型:
--
作者:
Delaney, Patrick M.;Browne, Duncan L.;Harrity, Joseph P. A.

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A [4+2] cycloaddition/retro-cycloaddition route to functionalised aromatic boronic esters is outlined. A range of electron deficient dienes (2-pyrones) and dienophiles (alkynylboronates) were found to participate in the reaction. Furthermore, high levels of regiocontrol could be obtained in this process and a consistent mode of alkyne insertion has been uncovered. (c) 2007 Elsevier Ltd. All rights reserved.