ACUTE LOWER RESPIRATORY-TRACT INFECTIONS IN NONHOSPITALIZED CHILDREN

ACUTE LOWER RESPIRATORY-TRACT INFECTIONS IN NONHOSPITALIZED CHILDREN
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DOI:
10.1016/s0022-3476(86)81034-4
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发表时间:
1986-05-01
影响因子:
5.1
通讯作者:
CLYDE, WA
CLYDE, WA
中科院分区:
医学2区
文献类型:
--
作者:
DENNY, FW;CLYDE, WA

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急性呼吸道感染是人类宿主最常见的感染,在儿科医生就诊的患者中占很大比例。虽然这些感染中的绝大多数涉及上呼吸道,但下呼吸道感染也足够频繁。几乎每天都会给医生带来问题。在所谓的发达国家,很明显,大多数儿童下呼吸道感染是由病毒或肺炎支原体引起的。不幸的是,一些LRI是由M以外的细菌引起的。肺炎,需要不同的抗菌治疗。问题是要区分哪些是由细菌引起的,应该用特定的抗生素治疗,哪些不是,只需要支持性治疗。检测微生物抗原的快速诊断技术将有助于确定病因。目前,这些技术还仅仅是研究工具,价格昂贵,只有少数大型医疗中心才能使用。医生可以选择治疗所有的LRI,因为它们可能有细菌来源或试图
Acute infections of the respiratory tract are the most common infections of the human host and account for a large proportion of patients seen by the practicing pediatrician? Although the great majority of these infections involve the upper respiratory tract, infections of the lower respiratory tract are sufficiently frequent as. to present almost daily problems to the physician. In so-called devel= oped countries it is apparent that most lower respiratory infections in Children are caused by viruses or Mycoplasma pneumoniae. Unfortunately, some LRIs are caused by bacteria other than M. pneumoniae and require different antimicrobial therapy. The problem is t9 distinguish those caused by bacteria that should be treated with a specific antibiotic from those that are not and require only supportive management.Rapid diagnostic techniques develoPed for the detection of microbial antigens will be of help in determining the cause. At present these techniques are iargely research tools, expenSive and available in only a few large medical centers. The physician has the choice of treating all LRIs because they might have a bacterial origin or attempting to