Synthesis of highly substituted 4H-pyrido[1,2-a]pyrimidines via a one-pot three-component condensation reaction.
Synthesis of highly substituted 4H-pyrido[1,2-a]pyrimidines via a one-pot three-component condensation reaction.
复制标题
DOI：
10.1021/co400086u
复制
发表时间：
2013-08
影响因子：
--
通讯作者：
Kai Yang;Jinbao Xiang;G. Bao;Q. Dang;X. Bai
中科院分区：
文献类型：
--
作者：
Kai Yang;Jinbao Xiang;G. Bao;Q. Dang;X. Bai
一锅三组分反应，包括在三氟甲磺酸催化下的2-氨基吡啶、醛和酮/醛的缩合，提供了快速获得高度取代的新型4 H-吡啶并[1，2-a]嘧啶的方法。
A one-pot three-component reaction, involving condensation of 2-aminopyridines, aldehydes, and ketones/aldehydes under trifluoromethanesulfonic acid catalysis, provides rapid access to highly substituted novel 4H-pyrido[1,2-a]pyrimidines.