AN ELECTRON MICROSCOPIC STUDY OF FERRITIN
AN ELECTRON MICROSCOPIC STUDY OF FERRITIN
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DOI：
10.1016/0006-3002(54)90376-5
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发表时间：
1954-01-01
期刊：
影响因子：
--
通讯作者：
FARRANT, JL
中科院分区：
文献类型：
--
作者：
FARRANT, JL
铁蛋白的电子显微镜研究表明，占蛋白质干重40%的氢氧化铁-磷酸铁络合物以胶束形式存在，直径约55A，由直径约27A的亚单位组成，胶束位于蛋白质分子内。某些间接证据，以前被解释为表明胶束位于蛋白质分子的表面，可以与电子显微镜证据相一致。铁蛋白和载脂蛋白分子直径的电子显微镜测定值与X射线衍射法和超速离心法测得的值基本一致。
Electron microscope studies of ferritin show that the ferric-hydroxide-phosphate complex which constitutes up to 40% of the dry weight of the protein exists as micelles about 55 A in diameter consisting of sub-units about 27 A in diameter and that the micelles are located within the protein molecules. Certain indirect evidence which was previously interpreted as showing that the micelles are located on the surfaces of the protein molecules can be reconciled with the electron microscope evidence. The electron microscope value for the molecular diameter of ferritin and apoferritin is in fair agreement with the values obtained by X-ray diffraction and ultra-centrifuge studies.