Reliability and validity of an assessment of usual phytoestrogen consumption (United States)
Reliability and validity of an assessment of usual phytoestrogen consumption (United States)
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DOI：
10.1007/s10552-005-0391-6
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发表时间：
2006-02-01
影响因子：
2.3
通讯作者：
Jones, K
中科院分区：
文献类型：
--
作者：
Horn-Ross, PL;Barnes, S;Jones, K
目的 评估食物频率问卷 (FFQ) 和旨在量化植物雌激素消耗量的数据库的信度和效度。 方法 本研究包括加州教师研究 (CTS) 队列的 195 名成员，他们在 10 个月的时间内完成了四次 24 小时饮食回忆、研究前和研究后 FFQ，并提供了两份 24 小时尿液样本。一项平行研究的参与者 (n=106)（以及退出长期研究的 18 名女性）完成了一次回忆和 FFQ，并提供了一份 24 小时尿液样本。使用液相色谱-质谱法测定尿液植物雌激素。分别使用 Shrout-Fleiss 类内相关性和能量调整去衰减 Pearson 相关性评估可靠性和有效性。结果 反映 FFQ 植物雌激素评估再现性的相关性范围为 0.67 至 0.81。主要植物雌激素化合物（即大豆黄酮、金雀异黄酮和开环异落叶松树脂醇）的有效性相关性（FFQ 与饮食回忆相比）范围为 0.67 至 0.79，不太常见的化合物的有效性相关性为 0.43 至 0.54。与尿液水平相比，异黄酮的有效性相关性范围为 0.41 至 0.55，总木脂素的有效性相关性范围为 0.16 至 0.21。 结论 我们的异黄酮评估具有重复性、有效性，并且是评估与非亚洲人群疾病风险关系的绝佳工具。在这些工具能够准确地用于评估木脂素消耗之前，还需要进一步的研究。
Objective To evaluate the reliability and validity of a food-frequency questionnaire (FFQ) and database designed to quantify phytoestrogen consumption.Methods This study included 195 members of the California Teachers Study (CTS) cohort who, over a 10-month period, completed four 24-h dietary recalls, a pre- and post-study FFQ, and provided two 24-h urine specimens. Participants (n=106) in a parallel study (and 18 women who dropped out of the long-term study) completed a single recall and FFQ, and provided one 24-h urine specimen. Urinary phytoestrogens were determined using liquid chromatography-mass spectrometry. Reliability and validity were evaluated using Shrout-Fleiss intraclass correlations and energy-adjusted deattenuated Pearson correlations, respectively.Results Correlations reflecting the reproducibility of the FFQ phytoestrogen assessment ranged from 0.67 to 0.81. Validity correlations (FFQ compared to dietary recalls) ranged from 0.67 to 0.79 for the major phytoestrogenic compounds (i.e., daidzein, genistein, and secoisolariciresinol) and 0.43 to 0.54 for the less common compounds. Compared to urinary levels, validity correlations ranged from 0.41 to 0.55 for the isoflavones and 0.16 to 0.21 for total lignans.Conclusion Our isoflavone assessment is reproducible, valid, and an excellent tool for evaluating the relationship with disease risk in non-Asian populations. Further research is needed before these tools can accurately be used to assess lignan consumption.