The functional neuroanatomy of simple and complex sequential finger movements: a PET study
The functional neuroanatomy of simple and complex sequential finger movements: a PET study
复制标题
DOI：
10.1093/brain/121.2.253
复制
发表时间：
1998-02-01
期刊：
影响因子：
14.5
通讯作者：
Hallett, M
中科院分区：
文献类型：
--
作者：
Catalan, MJ;Honda, M;Hallett, M
用PET测量局部脑血流量（rCBF），定位不同长度的简单重复性和顺序性手指运动所激活的脑区。实验设计包括0.5HZ听觉起搏提示的手指运动。在不同序列长度的所有条件下，对侧初级感觉运动和运动前区皮层，补充运动区和同侧小脑皮层被激活。这些区域显示出从休息到简单重复运动的激活大幅增加，并且随着最短序列的进一步增加，这表明艺术执行在运行序列中的作用。同侧运动前区（Brodmann 6区）、双侧顶叶后区（Brodmann 7区）和楔前叶的rCBF仅与序列的长度有关，而从静止到简单重复运动无任何变化。这些区域更多地选择性地与序列性能相关。这一发现与这些区域在空间工作记忆中存储运动序列的假设是一致的。我们的研究结果表明，连续的手指运动会招募具有不同功能的离散脑区。
The brain regions activated by simple repetitive and sequential finger movements of different length were localized by measuring regional cerebral blood flow (rCBF) with PET The experimental design consisted of finger movements cued by auditory pacing at 0.5 HZ. In all conditions of different sequence length the contralateral primary sensorimotor and premotor cortex, supplementary motor area and ipsilateral cerebellar cortex were activated. These areas showed a large increase in activation from rest to simple repetitive movement, and a further increase with the shortest sequence, suggesting art executive role in running sequences. The ipsilateral premotor area (Brodmann area 6), bilateral posterior parietal areas (Brodmann area 7) and precuneus showed art increase in rCBF related only to the length of the sequences, without any change from rest to simple repetitive movement. These areas are more selectively related to sequence performance. This finding is consistent with the hypothesis that these areas function in the storage of motor sequences in spatial working memory. Our results suggest that sequential finger movements recruit discrete sets of brain areas with different functions.