The autophagy gene product BEC-1 supports normal aging and neurodevelopment in Caenorhabditis elegans I
The autophagy gene product BEC-1 supports normal aging and neurodevelopment in Caenorhabditis elegans I
复制标题
自噬基因产物 BEC-1 支持秀丽隐杆线虫 I 的正常衰老和神经发育
作者：
Nicholas A. Ashley;A. Holgado
图 1 线虫 bec-1(ok691) 突变体的寿命较短。 (A) Bec-1 基因示意图以浅蓝色显示，bec-1(ok691) 缺失突变以黄色显示 (wormbase.org)。 (B) 存活胚胎致死率的纯合 bec-1(ok691) 突变体（下）和杂合对应物（上）的图像。 (C) 监测纯合 bec-1(ok691) 突变体、杂合 bec-1(ok691) 突变体和对照动物的寿命。绘制的数据为平均值±1 SEM，n=60。使用非参数 Kruskal-Wallis 进行统计分析 (p< .001)。
Figure 1 C. elegans bec-1(ok691) mutants have a shorter lifespan. (A) Schematic of bec-1 gene shown in light blue and bec-1(ok691) deletion mutation in yellow (wormbase.org). (B) Image of homozygous bec-1(ok691) mutant surviving embryonic lethality (bottom), and the heterozygous counterpart (top). (C) Lifespan of homozygous bec-1(ok691) mutants, heterozygous bec-1(ok691) mutants, and control animals were monitored. Data plotted are mean ± 1 SEM, n=60. Statistical analysis was performed using a non-parametric Kruskal-Wallis (p< .001).