[Studies on chemical components of Carthamus tinctorius petals].
[Studies on chemical components of Carthamus tinctorius petals].
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发表时间：
1998-08
期刊：
影响因子：
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通讯作者：
Y. Li;Q. Che
中科院分区：
文献类型：
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作者：
Y. Li;Q. Che
红花的花瓣。（菊科）提供了一个最重要的药物在传统中医药[1]用于治疗妇科疾病，心脏病和炎症[2]。已报道从这些花瓣中分离出红花素、红花黄色素A和B、红花素A和C、异红花素、异红花素、羟基红花黄色素A和色托明，以及几种新的黄酮类化合物和酚类化合物[3]。这些研究的继续导致了四种化合物的分离，包括一种新的黄酮苷。干燥的C.用95%乙醇提取，提取物在水和有机溶剂（石油醚和EtOAc）之间分配。将水级分进行Diaion D101和Sephadex LH-20柱色谱，通过EtOH在水中的梯度洗脱，得到化合物1-4。化合物1为6-羟基山萘酚3-O-葡萄糖苷，化合物2为新化合物6-羟基山萘酚7-O-葡萄糖苷，化合物3为山萘酚3-O-芸香糖苷，化合物4为槲皮素3-O-葡萄糖苷。
The flower petals of Carthamus tinctorius L. (Compositae) provide one of the most important drugs in traditional Chinese medicine[1] used for the treatment of gynecological diseases, heart diseases and inflammation[2]. Carthamin, safflor yellows A and B, safflomin A, and C, isocarthamin, isocarthamidin, hydroxysafflor yellow A, and tinctormine have been reported from these petals, as well as several new flavonoids and phenolic compounds[3]. A continuation of these studies has led to the isolation of four compounds including a new flavonoid glucoside. The dried petals of C. tinctorius, cultivated in Sichuan, China, were extracted with 95% ethanol, and the extract was partitioned between H2O and organic solvents (petroleum ether and EtOAc). The water fraction was subjected to Diaion D101 and Sephadex LH-20 column chromatography with elution by a gradient of EtOH in water to yield compounds 1-4. Compound I is 6-hydroxykaempferol 3-O-glucoside, compound II is a new compound named 6-hydroxykaempferol 7-O-glucoside, compound 3 is kaempferol 3-O-rutinoside and compound 4 is quercetin 3-O-glucoside.