On the driver of blood circulation beyond the heart.

On the driver of blood circulation beyond the heart.
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DOI:
10.1371/journal.pone.0289652
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发表时间:
2023
期刊:
影响因子:
3.7
通讯作者:
--
中科院分区:
综合性期刊3区
文献类型:
--
作者:

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心脏被广泛认为是血液循环的独特驱动力。最近,我们发现了一种流动驱动机制,可以在没有施加压力的情况下运行,使用红外(IR)能量来推动流动。我们考虑了这样一种可能性,即通过利用这种机制,血管本身可以推动血流。我们使用一个三日龄的鸡胚模型验证了这种驱动机制的存在。当心脏停止时,血液继续流动约50分钟,尽管速度较低。当引入IR时,死后血流从~41.1 ± 25.6 μm/s增加到~153.0 ± 59.5 μm/s(n = 6)。当IR能量在其他生理条件下减少时,血液无法流动。因此,这种依赖IR的、基于血管的流动驱动机制确实可以在循环系统中起作用,补充心脏的作用。
The heart is widely acknowledged as the unique driver of blood circulation. Recently, we discovered a flow-driving mechanism that can operate without imposed pressure, using infrared (IR) energy to propel flow. We considered the possibility that, by exploiting this mechanism, blood vessels, themselves, could propel flow. We verified the existence of this driving mechanism by using a three-day-old chick-embryo model. When the heart was stopped, blood continued to flow for approximately 50 minutes, albeit at a lower velocity. When IR was introduced, the postmortem flow increased from ~41.1 ± 25.6 μm/s to ~153.0 ± 59.5 μm/s (n = 6). When IR energy was diminished under otherwise physiological conditions, blood failed to flow. Hence, this IR-dependent, vessel-based flow-driving mechanism may indeed operate in the circulatory system, complementing the action of the heart.
DOI: 10.1073/pnas.95.26.15741
发表时间: 1998-12-22
影响因子: 11.1
作者:
Kleinfeld, D;Mitra, PP;Denk, W
通讯作者: Denk, W
DOI: 10.1002/ar.1091180406
发表时间: 1954-01-01
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