STRUCTURES OF A88696 C, D AND F - GASTRIC ATPASE INHIBITORS

STRUCTURES OF A88696 C, D AND F - GASTRIC ATPASE INHIBITORS
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DOI:
10.1016/s0040-4039(00)61494-6
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发表时间:
1993-12-03
影响因子:
1.8
通讯作者:
DEETER, JB
DEETER, JB
中科院分区:
化学4区
文献类型:
--
作者:
BONJOUKLIAN, R;MYNDERSE, JS;DEETER, JB

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对从核盘链霉菌中分离得到的A88696C(1)、D(2)和F(3)的结构进行了光谱分析。1和3是含有螺三硝酸的大环内酯类化合物,2是内酯环的α-位带有螺环氧化物的β-二酮基互变异构体。
The structures of A88696C (1), D (2) and F (3), isolated from Streptomyces sclerotialus, are described on the basis of spectroscopic analysis. 1 and 3 are spirotetronic acid-containing macrolides, and 2 is the beta-dicarbonyl tautomer with a spiroepoxide at the alpha-site of the lactone ring.