Tuberculous meningitis in HIV-infected patients: drug susceptibility and clinical outcome
Tuberculous meningitis in HIV-infected patients: drug susceptibility and clinical outcome
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DOI：
10.1097/qad.0b013e328012b84d
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发表时间：
2007-01-30
期刊：
影响因子：
3.8
通讯作者：
Ambroggi, Marta
中科院分区：
文献类型：
--
作者：
Cecchini, Diego;Ambrosioni, Juan;Ambroggi, Marta
本研究的目的是确定结核性脑膜炎（TM）患者死亡的预后因素，并显示多重耐药菌株感染对这种疾病的预后的影响。我们回顾性分析了1996年至2004年期间在我们机构就诊的培养确诊TM的艾滋病毒感染患者的临床图表。以下变量与住院期间的死亡相关：入院时的神经系统体征，C134 T细胞计数低于50个细胞/μ l和多药耐药菌株感染。
The objective of this study was to identify prognostic factors of death in patients with tuberculous meningitis (TM) and show the impact of infection by multidrug-resistant strains on the outcome of this disease. We retrospectively analysed clinical charts of HIV-infected patients with culture-confirmed TM attending our institution during 1996-2004. The following variables were associated with death during hospitalization: neurological signs at admission, a C134 T-cell count less than 50cells/mu l and infection by multidrug-resistant strains.