A challenge to diffuse optical tomography using the radiative transport equation

A challenge to diffuse optical tomography using the radiative transport equation
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DOI:
10.1109/iccme.2012.6275595
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发表时间:
2012-07
期刊:
2012 ICME International Conference on Complex Medical Engineering (CME)
影响因子:
--
通讯作者:
N. Oishi;H. Fukuyama
N. Oishi;H. Fukuyama
中科院分区:
其他
文献类型:
--
作者:
N. Oishi;H. Fukuyama

文献摘要

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扩散光学层析成像(DOT:Diffuse Optical Tomography)使用近红外光来重构组织的吸收系数和散射系数等光学特性的空间分布。光在散射介质中的传播由辐射传递方程(RTE)控制。然而,大多数研究依赖于扩散近似的RTE,因为它是困难和具有挑战性的数值求解。我们发展了RTE正问题的有效数值计算算法,并将计算结果与实际的体模实验结果进行了比较,揭示了漫射近似的局限性和RTE描述光在散射介质中传播的有效性。
Diffuse optical tomography (DOT) reconstructs the spatial distribution of optical properties such as an absorption coefficient and a scattering coefficient of the tissues using near-infrared light. Light propagation in a scattering medium is governed by the radiative transfer equation (RTE). However, most studies rely on the diffusion approximation of the RTE because it is difficult and challenging to solve numerically. We have developed the effective numerical calculation algorithms for the RTE forward problem and compared these results with those by the actual phantom experiments, which revealed the limits of the diffusion approximation and the validity of the RTE for describing light propagation in a scattering medium.