Pulmonary disease assessment in cystic fibrosis:: Comparison of CT scoring systems and value of bronchial and arterial dimension measurements
Pulmonary disease assessment in cystic fibrosis:: Comparison of CT scoring systems and value of bronchial and arterial dimension measurements
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DOI：
10.1148/radiol.2312021393
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发表时间：
2004-05-01
期刊：
影响因子：
19.7
通讯作者：
Tiddens, HAWM
中科院分区：
文献类型：
--
作者：
de Jong, PA;Ottink, MD;Tiddens, HAWM
目的：回顾性比较五种评分系统对囊性纤维化儿童肺部疾病的评估，并确定支气管和动脉尺寸测量的附加价值。材料与方法：比较五种薄层CT评分系统获得的评分。0分表示无异常；分数越高，意味着看到的结构异常越多。3名观察人员对25名囊性纤维化儿童的薄层CT扫描进行复查，评分间隔从1-2周到1-2个月不等，然后重新评分。用类内相关系数计算观察者间和观察者内信度。定量测量支气管和动脉的尺寸。薄层CT评分与支气管和动脉尺寸以及肺功能测试（PFTs）结果（如1秒用力呼气量（FEV1））相关（Spearman相关性）。结果：5种评分系统的评分均具有可重复性，类内相关系数为0.74及以上（P < 0.05），且与FEV1呈显著相关（R = -0.73 ~ -0.69, P < 0.01）。支气管直径与伴行肺动脉直径之比与薄层CT评分相关，但与FEV1无关。支气管壁厚与伴行肺动脉直径之比与薄层CT评分或PFT结果无关。结论：薄层CT评分具有重复性，且与PFT结果相关。支气管尺寸的测量与评分或PFT结果无显著相关性。(c) rsna， 2004年。
PURPOSE: To retrospectively compare thin-section computed tomographic (CT) scores obtained with five scoring systems for assessment of pulmonary disease in children with cystic fibrosis and to determine additional value of bronchial and arterial dimension measurements.MATERIALS AND METHODS: Scores obtained with five thin-section CT scoring systems were compared. A score of 0 indicated the absence of abnormalities; a higher score meant that more structural abnormalities were seen. Three observers assigned scores and then reassigned scores after intervals varying from 1-2 weeks to 1-2 months at review of thin-section CT scans obtained in 25 children with cystic fibrosis. Interobserver and intraobserver reliability was calculated with intraclass correlation coefficients. Quantitative measurements of bronchial and arterial dimensions were obtained. Thin-section CT scores were correlated (Spearman correlation) with bronchial and arterial dimensions and with results of pulmonary function tests (PFTs), such as forced expiratory volume in 1 second (FEV1).RESULTS: Scores with all five scoring systems were reproducible, with intraclass correlation coefficients of 0.74 and higher (P < .05), and showed significant correlations with FEV1 (R = -0.73 to -0.69, P < .01). Ratio of bronchial diameter to accompanying pulmonary arterial diameter was correlated with thin-section CT scores but not with FEV1 Ratio of bronchial wall thickness to accompanying pulmonary arterial diameter was not correlated with thin-section CT scores or PFT results.CONCLUSION: Thin-section CT scores were reproducible and were correlated with PFT results. Measurements of bronchial dimensions were not significantly related to scores or PFT results. (C) RSNA, 2004.