Patient Perception of Disease-Related Symptoms and Complications in Relapsing Polychondritis
Patient Perception of Disease-Related Symptoms and Complications in Relapsing Polychondritis
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DOI：
10.1002/acr.23492
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发表时间：
2018-08-01
影响因子：
4.7
通讯作者：
Katz, James D.
中科院分区：
文献类型：
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作者：
Ferrada, Marcela A.;Grayson, Peter C.;Katz, James D.
Objective.评估复发性多囊卵巢炎（RP）患者报告的症状和疾病负担。RP患者完成了疾病特异性在线调查，以确定归因于疾病的症状。根据是否存在耳/鼻、气道或关节受累将患者分为亚组。在每个亚组中评估诊断、治疗和疾病相关并发症的途径。304名受访者的数据被纳入本分析。在诊断之前，大多数RP患者去急诊室（54%），看过> 3名医生（54%），症状持续>5年（64%）。同时诊断纤维肌痛和无耳/鼻或关节受累与诊断延迟>1年相关。RP诊断前的常见诊断包括气道受累患者的哮喘（35%对22%; P = 0.03）和耳/鼻受累患者的耳部感染（51%对6%; P
Objective. To assess patient-reported symptoms and burden of disease in relapsing polychondritis (RP).Methods. Patients with RP completed a disease-specific online survey to identify symptoms attributed to illness. Patients were divided into subgroups based upon presence or absence of ear/nose, airway, or joint involvement. Pathway to diagnosis, treatment, and disease-related complications were assessed within each subgroup.Results. Data from 304 respondents were included in this analysis. Prior to diagnosis, most patients with RP went to the emergency room (54%), saw > 3 physicians (54%), and had symptoms for >5 years (64%). A concomitant diagnosis of fibromyalgia and absence of ear/nose or joint involvement was associated with diagnostic delay >1 year. Common diagnoses prior to RP diagnosis included asthma in patients with airway involvement (35% versus 22%; P = 0.03) and ear infection in patients with ear/nose involvement (51% versus 6%; P