Suppression of thyroarytenoid muscle responses during repeated air pressure stimulation of the laryngeal mucosa in awake humans
Suppression of thyroarytenoid muscle responses during repeated air pressure stimulation of the laryngeal mucosa in awake humans
复制标题
DOI：
10.1177/000348940511400403
复制
发表时间：
2005-04-01
影响因子：
1.4
通讯作者：
Ludlow, CL
中科院分区：
文献类型：
--
作者：
Kearney, PR;Poletto, CJ;Ludlow, CL
重复刺激喉粘膜发生在讲话。然而，单一刺激可引起喉内收肌反应（LAR）。我们的假设是，在人类中，对重复快速气压刺激的LAR受到中枢抑制。将钩丝电极插入两侧的甲杓肌和环甲肌，一侧插入环杓后肌。成对的喷气刺激的粘膜在杓状软骨的压力水平的三倍阈值与刺激间隔从250到5,000毫秒。双边甲杓反应发生在150毫秒左右，超过70%的初始刺激。以2秒或更短的时间间隔重复呈现，发生率降低到40%以下，反应幅度降低了50%。内收肌对重复吹气刺激的反应的中枢抑制可能允许说话者在不引起可能中断讲话的反射性痉挛的情况下产生声音。
Repeated stimulation of the laryngeal mucosa occurs during speech. Single stimuli, however, can elicit the laryngeal adductor response (LAR). Our hypothesis was that the LAR to repeated rapid air pressure stimuli is centrally suppressed in humans. Hooked-wire electrodes were inserted into the thyroarytenoid and cricothyroid muscles on both sides and into the posterior cricoarytenoid muscle on one side. Pairs of air puff stimuli were presented to the mucosa over the arytenoids at pressure levels three times threshold with interstimulus intervals from 250 to 5,000 ms. Bilateral thyroarytenoid responses occurred at around 150 ms to more than 70% of the initial stimuli. With repeated presentation at intervals of 2 seconds or less, the percent occurrence decreased to less than 40% and response amplitudes were reduced by 50%. Central suppression of adductor responses to repeated air puff stimuli may allow speakers to produce voice without eliciting reflexive spasms that could disrupt speech.