Analysis of energy sources for Mycoplasma penetrans gliding motility.
Analysis of energy sources for Mycoplasma penetrans gliding motility.
复制标题
穿透支原体滑行运动的能量来源分析。
DOI：
10.1111/1574-6968.12026
复制
发表时间：
2013
影响因子：
2.1
通讯作者：
Balish,MitchellF
中科院分区：
文献类型：
--
作者：
Jurkovic,DominikaA;Hughes,MichaelR;Balish,MitchellF
反式支原体是一种主要在HIV感染者中发现的潜在人类病原体，它使用尖端结构进行粘附和滑动运动。为加深对M.为了确定M的运动性，我们使用了与其他生物运动性相关的能量源的化学抑制剂来确定M使用的是哪种能量源。Mycoplasma transgliding motility在质子动力抑制剂、钠动力抑制剂或消耗细胞ATP的试剂存在下不会被消除。在接近中性的pH值下，滑动速度随着温度的升高而增加。没有一个明确的化学能源的滑翔运动和速度和温度之间的正相关性表明，来自热的能量提供了主要的动力来源的滑翔马达ofM。是的。
Mycoplasma penetrans, a potential human pathogen found mainly in HIV-infected individuals, uses a tip structure for both adherence and gliding motility. To improve our understanding of the molecular mechanism ofM. penetransgliding motility, we used chemical inhibitors of energy sources associated with motility of other organisms to determine which of these is used byM. penetransand also tested whether gliding speed responded to temperature and pH.Mycoplasma penetransgliding motility was not eliminated in the presence of a proton motive force inhibitor, a sodium motive force inhibitor, or an agent that depletes cellular ATP. At near-neutral pH, gliding speed increased as temperature increased. The absence of a clear chemical energy source for gliding motility and a positive correlation between speed and temperature suggest that energy derived from heat provides the major source of power for the gliding motor ofM. penetrans.