Differential hedonic experience and behavioral activation in schizophrenia and bipolar disorder.
Differential hedonic experience and behavioral activation in schizophrenia and bipolar disorder.
复制标题
精神分裂症和双相情感障碍的差异享乐体验和行为激活。
DOI：
10.1016/j.psychres.2014.06.030
复制
发表时间：
2014
影响因子：
11.3
通讯作者：
Taylor,StephanF
中科院分区：
文献类型：
--
作者：
Tso,IvyF;Grove,TylerB;Taylor,StephanF
克雷佩林式的精神分裂症（SZ）和双相情感障碍（BP）之间的区别强调了前者的情感和意志障碍，但直接比较这两种疾病的享乐体验的数据很少。这项研究检验了享乐体验和行为激活是否可能是区分 SZ 和 BP 的有用表型。参与者包括 39 名 SZ 患者和 24 名 BP 患者，当前没有与人口统计学和负面影响相匹配的情绪发作，以及 36 名健康对照 (HC)。他们完成了查普曼身体和社交快感缺失量表、愉悦时间体验量表（TEPS）和行为激活量表（BAS）。与 HC 相比，SZ 和 BP 的自我报告负面情绪和特质快感缺乏水平同样升高。然而，SZ 报告的快乐体验 (TEPS) 和行为激活 (BAS) 显着低于 BP，而 BP 与 HC 没有差异。 SZ 和 BP 显示了享乐体验和行为激活测量之间关系的不同模式。总体而言，结果表明，即使情感症状很小时，享乐体验和行为激活的减少也可能是区分 SZ 和 BP 的有效表型。然而，SZ 和 BP 之间的快感体验差异对测量策略很敏感，需要进一步研究快感缺失的性质及其与这些疾病的动机的关系。
The Kraepelinian distinction between schizophrenia (SZ) and bipolar disorder (BP) emphasizes affective and volitional impairment in the former, but data directly comparing the two disorders for hedonic experience are scarce. This study examined whether hedonic experience and behavioral activation may be useful phenotypes distinguishing SZ and BP. Participants were 39 SZ and 24 BP patients without current mood episode matched for demographics and negative affect, along with 36 healthy controls (HC). They completed the Chapman Physical and Social Anhedonia Scales, Temporal Experience of Pleasure Scale (TEPS), and Behavioral Activation Scale (BAS). SZ and BP showed equally elevated levels of self-report negative affect and trait anhedonia compared to HC. However, SZ reported significantly lower pleasure experience (TEPS) and behavioral activation (BAS) than BP, who did not differ from HC. SZ and BP showed differential patterns of relationships between the hedonic experience and behavioral activation measures. Overall, the results suggest that reduced hedonic experience and behavioral activation may be effective phenotypes distinguishing SZ from BP even when affective symptoms are minimal. However, hedonic experience differences between SZ and BP are sensitive to measurement strategy, calling for further research on the nature of anhedonia and its relation to motivation in these disorders.