Detection of Hepatocellular Carcinoma: Gadoxetic Acid-Enhanced 3-Dimensional Magnetic Resonance Imaging Versus Multi-Detector Row Computed Tomography
Detection of Hepatocellular Carcinoma: Gadoxetic Acid-Enhanced 3-Dimensional Magnetic Resonance Imaging Versus Multi-Detector Row Computed Tomography
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DOI：
10.1097/rct.0b013e3181a7e3c7
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发表时间：
2009-11-01
影响因子：
1.3
通讯作者：
Yu, Hee Chul
中科院分区：
文献类型：
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作者：
Kim, Young Kon;Kim, Chong Soo;Yu, Hee Chul
目的：本研究的目的是比较加多喜酸增强磁共振成像（MRI）与多排计算机断层扫描（MDCT）诊断肝细胞癌（hcc）的准确性和敏感性。材料：本研究纳入了62例（81例hcc）患者，他们使用三维体积内插技术进行MDCT和gadoxetic酸增强MRI检查，平均间隔7天（范围3-11天）。两位观察员就……达成了共识。2组图像：gadoxetic酸组（未增强、早期动态、10分钟和20分钟肝细胞期图像）和3期MDCT诊断的准确性和敏感性采用无替代反应受者操作特征法进行评估。结果：与MDCT（0.930）相比，gadoxetic酸组（0.963）的受试者工作特征曲线（Az值）下面积有增大的趋势，但差异无统计学意义（P = 0.41）。gadoxetic酸组的敏感性（91.4%）优于MDCT （71.6%, P = 0.0001）。有12个病变在MDCT上仅显示动脉血管增生，但在加多乙酸组上显示动脉血管增生和迟发性低密度。结论：加多西酸增强MRI，包括肝细胞期成像，对hcc的检测比MDCT更敏感。
Purpose: The aim of this study was to compare the diagnostic accuracy and sensitivity of gadoxetic acid-enhanced magnetic resonance imaging (MRI) with multi-detector row computed tomography (MDCT) for the detection of hepatocellular carcinomas (HCCs).Materials: Sixty-two patients (81 HCCs) who underwent MDCT and gadoxetic acid-enhanced MRI using a 3-dimensional volumetric interpolated technique with a mean interval of 7 days (range, 3-11 days) were included in this study. Two observers reached a consensus on. 2 sets of images: the gadoxetic acid set (unenhanced, early dynamic, 10-minute, and 20-minute hepatocyte phase images) and the 3-phase MDCT Diagnostic accuracy and sensitivity were evaluated using the alternative-free response receiver operating characteristic method.Results: There was a trend toward increased area under the receiver operating characteristic curve (Az value) for the gadoxetic acid set (0.963) as compared with the MDCT (0.930), but no significant difference was found (P = 0.41). Sensitivity of the gadoxetic acid set (91.4%) was better than that of the MDCT (71.6%; P = 0.0001). There were 12 lesions that showed only arterial hypervascularization on MDCT but showed arterial hypervascularization and delayed hypointensity on the gadoxetic acid set.Conclusions: Gadoxetic acid-enhanced MRI, including hepatocyte phase imaging, is more sensitive than MDCT for the detection of HCCs.