Evaluation of translation in the normal and dysplastic hip using three-dimensional magnetic resonance imaging and voxel-based registration
Evaluation of translation in the normal and dysplastic hip using three-dimensional magnetic resonance imaging and voxel-based registration
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DOI：
10.1016/j.joca.2011.01.017
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发表时间：
2011-06-01
影响因子：
7
通讯作者：
Sugamoto, K.
中科院分区：
文献类型：
--
作者：
Akiyama, K.;Sakai, T.;Sugamoto, K.
目的：通过磁共振成像(MRI)评价股骨头中心(FHC)在不同髋关节位置的三维平移，通过比较正常髋关节和髋臼发育不良患者的髋关节，阐明体内髋关节的不稳定性。设计：正常髋关节40个，发育不良女性髋关节22个。磁共振成像在四种不同的位置进行：中立位、屈曲45度、伸展15度和Patrick位。分别在中性位置提取股骨和骨盆骨骼，并使用基于体素的配准将其叠加到每个不同位置的图像上。中立位时髋臼中心至FHC的距离定义为三维移位。将FHC在中立位与各不同位置的距离定义为三维平移。结果：中心边缘(CE)角是3D移位的决定因素(β=-0.415，P=0.001)，正常女性髋关节与发育不良髋关节3D移位差异有统计学意义(P=0.047)。从中立位到Patrick位，正常组和发育不良组髋关节FHC分别向后下方移位1.12±0.39 mm(0.45~1.85 mm)和1.97±0.84 mm(0.95~4.34 mm)，组间差异有统计学意义(P=0.005)。Ce角是从中立位到Patrick位3D平移的决定因素(β=-0.730，P<；0.001)。在3D平移中，观察者内和观察者间重复性的平均均方根误差分别为0.172 mm和0.193 mm。结论：髋关节不稳定程度与髋臼发育不良程度成比例增加。一种基于3D MRI体素的配准技术可以在不暴露于放射性的情况下显示天然髋关节的活体形态和运动学。(C)2011年国际骨性关节炎研究会。爱思唯尔有限公司出版。保留所有权利。
Objective: To elucidate in vivo hip instability by comparing normal hips to hips with acetabular dysplasia by evaluating three-dimensional (3D) translations of the femoral head center (FHC) at different hip positions using magnetic resonance imaging (MRI).Design: Forty normal hips and 22 dysplastic female hips were examined. MRI was performed at four different positions bilaterally: neutral, 45 degrees of flexion, 15 degrees of extension, and the Patrick position. Femoral and pelvic bones were separately extracted at the neutral position and superimposed over the images of each different position using voxel-based registration. The distance between the acetabular center and FHC at neutral position was defined as 3D-migration. The distance between FHC at neutral position and that at each different position was defined as 3D-translation. Two-way repeated measures analysis of variance was performed to consider the dependency between right and left-side data, and multiple linear regression analyses were performed to assess independent relationships.Results: The center-edge (CE) angle was the determinant for 3D-migration (beta = -0.415, P = 0.001), and there was a statistical significant difference in 3D-migration between normal female hips and dysplastic hips (P = 0.047). From neutral to the Patrick position, the FHC of normal and dysplastic hips translated postero-infero-medially by 1.12 +/- 0.39 mm (0.45-1.85 mm) and 1.97 +/- 0.84 mm (0.95-4.34 mm), respectively, and the difference between the groups was statistically significant (P = 0.005). CE angle was the determinant for 3D-translation from neutral to the Patrick position (beta = -0.730, P < 0.001). The average root mean square error in 3D-translation was 0.172 mm and 0.193 mm for intra- and interobserver reproducibility, respectively.Conclusions: Hip instability was increased in proportion to the severity of acetabular dysplasia. A 3D MRI voxel-based registration technique can show in vivo morphology and kinematics of the native hip without exposure to radioactivity. (C) 2011 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.