Sudden cardiac death is associated both with epilepsy and with use of antiepileptic medications
Sudden cardiac death is associated both with epilepsy and with use of antiepileptic medications
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DOI：
10.1136/heartjnl-2014-305664
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发表时间：
2015-01-01
期刊：
影响因子：
5.7
通讯作者：
Tan, Hanno L.
中科院分区：
文献类型：
--
作者：
Bardai, Abdennasser;Blom, Marieke T.;Tan, Hanno L.
目的癫痫与心源性猝死（SCD）的危险性增加有关。我们的目的是建立，在一个社区为基础的研究，无论是介导的癫痫本身，使用抗癫痫药物（AEMs），或both.Methods我们研究了SCD病例和年龄/性别匹配的对照组在一个大型的全科医生的研究数据库（n=478 661例）的病例对照研究。症状性癫痫（癫痫发作）的SCD风险
Objective Epilepsy is associated with increased risk for sudden cardiac death (SCD). We aimed to establish, in a community based study, whether this association is mediated by epilepsy per se, use of antiepileptic medications (AEMs), or both.Methods We studied SCD cases and age/sex matched controls in a case-control study in a large scale general practitioners' research database (n=478 661 patients). SCD risk for symptomatic epilepsy (seizure