Dynamic nanoimaging of extended objects via hard X-ray multiple-shot coherent diffraction with projection illumination optics
Dynamic nanoimaging of extended objects via hard X-ray multiple-shot coherent diffraction with projection illumination optics
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DOI：
10.1038/s42005-021-00539-x
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发表时间：
2021-03
影响因子：
5.5
通讯作者：
Y. Takayama;Keizo Fukuda;Motoki Kawashima;Yuki Aoi;Daiki Shigematsu;Tatsuki Akada;Takumi Ikeda
中科院分区：
文献类型：
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作者：
Y. Takayama;Keizo Fukuda;Motoki Kawashima;Yuki Aoi;Daiki Shigematsu;Tatsuki Akada;Takumi Ikeda
对材料特性和生物细胞功能的结构机制的探索导致了相干衍射成像 (CDI) 及其在硬 X 射线领域的变体的积极发展。在此，我们提出了多镜头 CDI，这是一种全场 CDI 技术，致力于以超出当前仪器限制的时空分辨率可视化扩展对象中的局部纳米结构动力学。多次拍摄 CDI 从时间演化的衍射图案中重建了局部动态的“电影”，这与强大的扫描变体、叠层照相术兼容。我们开发了投影照明光学器件，以生产具有明确照明区域和相位检索算法的探头，为动态图像的可靠重建建立了时空平滑度约束。使用同步加速器硬 X 射线的数值模拟和概念验证实验证明了以 10Hz 或更高的帧速率可视化动态纳米结构物体的能力。
The quest for understanding the structural mechanisms of material properties and biological cell functions has led to the active development of coherent diffraction imaging (CDI) and its variants in the hard X-ray regime. Herein, we propose multiple-shot CDI, a full-field CDI technique dedicated to the visualisation of local nanostructural dynamics in extended objects at a spatio-temporal resolution beyond that of current instrumentation limitations. Multiple-shot CDI reconstructs a “movie” of local dynamics from time-evolving diffraction patterns, which is compatible with a robust scanning variant, ptychography. We developed projection illumination optics to produce a probe with a well-defined illumination area and a phase retrieval algorithm, establishing a spatio-temporal smoothness constraint for the reliable reconstruction of dynamic images. The numerical simulations and proof-of-concept experiment using synchrotron hard X-rays demonstrated the capability of visualising a dynamic nanostructured object at a frame rate of 10 Hz or higher.