Potential adverse effects of COVID19 vaccines among Iraqi population; a comparison between the three available vaccines in Iraq; a retrospective cross-sectional study.

Potential adverse effects of COVID19 vaccines among Iraqi population; a comparison between the three available vaccines in Iraq; a retrospective cross-sectional study.
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DOI:
10.1016/j.dsx.2021.102207
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发表时间:
2021-09
期刊:
Diabetes & metabolic syndrome
影响因子:
--
通讯作者:
Merza MA
Merza MA
中科院分区:
其他
文献类型:
--
作者:
Almufty HB;Mohammed SA;Abdullah AM;Merza MA

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本研究的目的是揭示服用COVID-19疫苗后的潜在副作用,与严重副作用相关的风险因素,并比较伊拉克可用的三种COVID-19疫苗(国药集团,阿斯利康-牛津和辉瑞- BioNTech)。2021年4月进行了一项随机横断面研究。利用标准化问卷平台收集有关伊拉克人口的信息。1012例入组研究,60.2%为男性,39.8%为女性。84%的人在接种疫苗后出现症状。年轻受试者、女性、有COVID 19感染史受试者、有共病受试者和接种阿斯利康疫苗受试者是接种后发生不良反应的统计学显著性危险因素,P值分别为0.03、0.028、0.007、0.019和0.0001。关于症状的严重程度,大多数症状为轻度和中度。居住在伊拉克库尔德斯坦地区和接种阿斯利康疫苗是出现严重症状的危险因素,两者P值均< 0.0001。女性是D-二聚体升高的相关风险因素,P值= 0.05。疲劳、注射部位反应、发热、肌痛、头痛和寒战是报告最多的副作用。大多数症状的严重程度为轻度至中度。
the objectives of this study are to reveal the potential side effects after taking the covid19 vaccines, associated risk factors with severe side effects, and to compare the three COVID-19 vaccines available in Iraq (Sinopharm, AstraZeneca-Oxford and Pfizer- BioNTech). a randomized cross-sectional study was conducted in April 2021. A standardized questionnaire platform was utilized to collect information about the Iraqi population. 1012 were enrolled in the study, 60.2% were male and 39.8% were female. 84% were symptomatic post vaccination. Young aged participants, females, participants with history of COVID19 infection, those with comorbid diseases and AstraZeneca vaccine receivers were statistically significant risk factors for having adverse reactions post vaccination, P value (0.03, 0.028, 0.007, 0.019 and 0.0001) respectively. Regarding severity of symptoms, most symptoms were mild and moderate. Residency in Kurdistan Region of Iraq and AstraZeneca vaccine were the statistically significant risk factors for getting severe symptoms P value < 0.0001 of both. Females were an associated risk factor for D-dimer elevation P value = 0.05. fatigue, injection site reactions, fever, myalgia, headache and chills were the most reported side effects. Most symptoms were mild to moderate in term of severity.
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