Multiple-Scattering-Free Optical Glucose Monitoring Based on Femtosecond Pulse Interferometry
Multiple-Scattering-Free Optical Glucose Monitoring Based on Femtosecond Pulse Interferometry
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DOI：
10.1109/cleopr.2003.1277017
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发表时间：
2003-12
期刊：
影响因子：
1.2
通讯作者：
Y. Hori;T. Yasui;T. Araki
中科院分区：
文献类型：
--
作者：
Y. Hori;T. Yasui;T. Araki
我们设计了一种基于飞秒脉冲干涉技术的新型无多重散射光学葡萄糖监测系统。葡萄糖浓度通过飞行时间法测定，而多重散射光被相干门拒绝。对于 1.0% 脂肪乳溶液散射介质中的生理等效葡萄糖浓度，所得准确度和精密度分别为 94.7 和 24.5 mg/dl，而不含散射介质的参考样品的准确度和精密度分别为 65.3 和 23.8 mg/dl。比较这些结果，我们得出结论，所提出的方法对于散射介质中的葡萄糖测量是有效的。
We have designed a novel multiple-scattering-free optical glucose monitoring system based on femtosecond pulse interferometry. The glucose concentration is determined by a time-of-flight method, while multiple-scattering light is rejected by a coherence gate. The resultant accuracy and precision were 94.7 and 24.5 mg/dl, respectively, for physiological-equivalent glucose concentrations in a scattering medium of 1.0% intralipid solution, while the accuracy and precision for a reference sample containing no scattering medium were 65.3 and 23.8 mg/dl, respectively. Comparing these results, we conclude that the proposed method is effective for glucose measurement in a scattering medium.