Case report of a 69-year-old woman with double cancers: Primary yolk sac tumor of the right ovary and primary serous surface papillary carcinoma of the peritoneum
Case report of a 69-year-old woman with double cancers: Primary yolk sac tumor of the right ovary and primary serous surface papillary carcinoma of the peritoneum
复制标题
69岁女性双癌一例：右侧卵巢原发性卵黄囊瘤和腹膜原发性浆液性表面乳头状癌
DOI：
10.1007/bf02348388
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发表时间：
1996
影响因子：
3.3
通讯作者：
Y. Takeda
中科院分区：
文献类型：
--
作者：
K. Takizawa;T. Kawana;Shigeko Kakinoki;R. Saito;Y. Takeda
这是一个非常罕见的情况下，69岁的妇女与卵黄囊瘤的右侧卵巢和浆液性表面乳头状癌（SSPC）的腹膜报告。根据日本病理学会和日本妇产科学会的分类，对两种肿瘤进行组织学诊断。为了确认组织学诊断，进行了甲胎蛋白（AFP）和癌胚抗原（CEA）的免疫细胞化学研究以及AFP、CEA、CA 19 -9和CA 125的免疫组织化学研究。连续测定血清AFP和CA 125水平。在苏木精和伊红染色中，在右侧卵巢肿瘤中观察到与Schiller-Duval小体相关的内胚窦图案。然而，在几乎正常大小的左侧卵巢表面和网膜转移结节中发现乳头状浆液性癌。
This extremely rare case of a 69-year-old woman with yolk sac tumor of the right ovary and serous surface papillary carcinoma (SSPC) of the peritoneum is reported. Histological diagnosis for both tumors was done according to the classifications of the Japanese Society of Pathology and Japan Society of Obstetrics and Gynecology. To confirm the histological diagnosis, both immunocytochemical studies for alphafetoprotein (AFP) and carcinoembryonic antigen (CEA), and immunohistochemical studies for AFP, CEA, CA19-9, and CA125 were performed. Serum AFP and CA125 levels were serially determined. On hematoxylin and eosin staining an endodermal sinus pattern associated with Schiller-Duval bodies was observed in the right ovarian tumor. However, papillary serous carcinoma was found on the surface of the almost normal sized left ovary and in the omental metastatic nodules.