Leucophyllinines A and B, bisindole alkaloids from Leuconotis eugeniifolia
Leucophyllinines A and B, bisindole alkaloids from Leuconotis eugeniifolia
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DOI：
10.1007/s11418-019-01297-5
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发表时间：
2019-06-01
影响因子：
3.3
通讯作者：
Morita, Hiroshi
中科院分区：
文献类型：
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作者：
Tang, Yiming;Nugroho, Alfarius Eko;Morita, Hiroshi
从大叶白坚木（Leuconotis eugeniifolia）的树皮中分离出两种新的双吲哚生物碱，即由长春蔓胺型和白坚木胺型骨架组成的白叶碱A（1）和白叶碱B（2），并根据光谱数据阐明了它们的结构。白叶碱A和白叶碱B对恶性疟原虫3D7显示出抗疟原虫活性。
Two new bisindole alkaloids, leucophyllinines A (1) and B (2) consisting of eburnane and quebrachamine-type skeletons were isolated from the bark of Leuconotis eugeniifolia, and their structures were elucidated on the basis of spectroscopic data. Leucophyllinines A and B showed antiplasmodial activities against Plasmodium falciparum 3D7.