A FURTHER EXAMINATION OF THE EFFECTS OF SERTRALINE ON VOLUNTARY ETHANOL-CONSUMPTION
A FURTHER EXAMINATION OF THE EFFECTS OF SERTRALINE ON VOLUNTARY ETHANOL-CONSUMPTION
复制标题
DOI：
10.1016/0741-8329(88)90020-1
复制
发表时间：
1988-09-01
期刊：
影响因子：
2.3
通讯作者：
AMIT, Z
中科院分区：
文献类型：
--
作者：
GILL, K;FILION, Y;AMIT, Z
以前的研究表明，血清素吸收阻滞剂舍曲林抑制了乙醇和糖精的消耗，也抑制了体重的增加。有越来越多的证据表明，许多肾上腺素能药物，如激动剂，释放剂和摄取阻滞剂，减少食物摄入。发现舍曲林具有强有力的降血压作用。在本文中，证据支持的假设，即管理的5-羟色胺摄取阻滞剂减少乙醇的消耗作为一个次要的后果，抑制食物摄入。
Previous work with the serotonin uptake blocker, sertraline, demonstrated that the drug suppressed the consumption of ethanol and saccharin as well as body weight gain. There is increasing evidence that many serotonergic agents such as agonists, releasing agents and uptake blockers, reduce food intake. Sertraline was found to have a robust anorexic action. In this paper evidence is presented which supports the hypothesis that the administration of serotonin uptake blockers reduce ethanol consumption as a secondary consequence of a suppression in food intake.