H3K36 methyltransferase SDG708 enhances drought tolerance by promoting abscisic acid biosynthesis in rice
H3K36 methyltransferase SDG708 enhances drought tolerance by promoting abscisic acid biosynthesis in rice
复制标题
H3K36甲基转移酶SDG708通过促进水稻脱落酸生物合成增强耐旱性
DOI：
10.1111/nph.17290
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发表时间：
2021-03-25
期刊：
影响因子：
9.4
通讯作者：
Dong, Aiwu
中科院分区：
文献类型：
--
作者：
Chen, Kai;Du, Kangxi;Dong, Aiwu
染色质修饰在植物对非生物胁迫的适应中起着重要的作用，但组蛋白H3赖氨酸36（H3K36）甲基化在耐旱性中的确切作用尚不清楚。SDG708通过直接靶向激活脱落酸（阿坝）生物合成关键基因九顺式环氧胡萝卜素二加氧酶3（OsNCED3）和九顺式环氧胡萝卜素二加氧酶5（OsNCED5）来促进阿坝生物合成，并诱导保卫细胞过氧化氢积累，促进气孔关闭，减少水分损失。SDG708基因的过表达增强了水稻的耐旱性，提高了正常和干旱胁迫条件下的产量，因此，SDG708基因在水稻产量改良育种中具有潜在的表观遗传调节作用。
Chromatin modifications play important roles in plant adaptation to abiotic stresses, but the precise function of histone H3 lysine 36 (H3K36) methylation in drought tolerance remains poorly evaluated.Here, we report that SDG708, a specific H3K36 methyltransferase, functions as a positive regulator of drought tolerance in rice. SDG708 promoted abscisic acid (ABA) biosynthesis by directly targeting and activating the crucial ABA biosynthesis genes NINE-CIS-EPOXYCAROTENOID DIOXYGENASE 3 (OsNCED3) and NINE-CIS-EPOXYCAROTENOID DIOXYGENASE 5 (OsNCED5).Additionally, SDG708 induced hydrogen peroxide accumulation in the guard cells and promoted stomatal closure to reduce water loss. Overexpression of SDG708 concomitantly enhanced rice drought tolerance and increased grain yield under normal and drought stress conditions.Thus, SDG708 is potentially useful as an epigenetic regulator in breeding for grain yield improvement.