RE: "ASSOCIATIONS OF ELECTRIC SHOCK AND EXTREMELY LOW-FREQUENCY MAGNETIC FIELD EXPOSURE WITH THE RISK OF AMYOTROPHIC LATERAL SCLEROSIS: THE EURO-MOTOR PROJECT"
RE: "ASSOCIATIONS OF ELECTRIC SHOCK AND EXTREMELY LOW-FREQUENCY MAGNETIC FIELD EXPOSURE WITH THE RISK OF AMYOTROPHIC LATERAL SCLEROSIS: THE EURO-MOTOR PROJECT"
复制标题
回复：“电击和极低频磁场暴露与肌萎缩侧索硬化症风险的关联：欧洲电机项目”
DOI：
10.1093/aje/kwz122
复制
发表时间：
2019
影响因子：
5
通讯作者：
Chen Guangdi
中科院分区：
文献类型：
--
作者：
Su Liling;Jin Yumin;Lou Haifeng;Chen Guangdi
在最近的一篇文章中，Peters et al. (1)在3个欧洲国家（2010-2015年）的基于人群的病例对照研究中，研究了极低频磁场（ELF-MF）和电击终身职业暴露与肌萎缩侧索硬化症（ALS）风险的相关性。基于工作暴露矩阵（JEM）评估，作者发现曾经暴露于ELF-MF（比值比= 1.16，95%置信区间：1.01，1.33）和曾经潜在暴露于高于背景水平的电击（比值比= 1.23，95%置信区间：1.05，1.43）与ALS风险相关（1）。这些研究结果是有趣的，并支持可能的独立协会职业暴露于ELFMF和电击与ALS的风险。之前，我们对ELF-MF暴露与ALS风险之间的关联进行了荟萃分析，发现在通过电气职业的职称估计暴露水平的研究中，ALS风险略有但显着增加，但不是那些通过JEM估计暴露的研究（2）。通过汇集最近研究的数据，我们的荟萃分析显示，ALS风险增加与以下因素相关：
In a recent article, Peters et al.(1) investigated the associations of lifetime occupational exposure to extremely lowfrequency magnetic fields (ELF-MF) and electric shocks with risk of amyotrophic lateral sclerosis (ALS) in population-based case-control studies from 3 European countries (2010–2015). Based on job-exposure matrix (JEM) assessment, the authors found that both ever exposure to ELF-MF (odds ratio= 1.16, 95% confidence interval: 1.01, 1.33) and ever potential exposure to electric shocks above background level (odds ratio= 1.23, 95% confidence interval: 1.05, 1.43) were associated withALS risk (1). These findings are interesting and support possible independent associations of occupational exposure to ELFMF and electric shocks with ALS risk. Previously, we performed a meta-analysis of the association between ELF-MF exposure and ALS risk and found a slight but significant increase in ALS risk among studies that estimated exposure level by the job title of electrical occupations, but not those that estimated exposure by a JEM (2). By pooling data from the most recent studies, our meta-analysis showed that increased risk of ALS was associated with