High correlation between the bacterial species in denture plaque and pharyngeal microflora.
High correlation between the bacterial species in denture plaque and pharyngeal microflora.
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DOI：
10.1111/j.1741-2358.2003.00084.x
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发表时间：
2003-12-01
期刊：
影响因子：
2
通讯作者：
Miyamoto, Hiroshi
中科院分区：
文献类型：
--
作者：
Sumi, Yasunori;Kagami, Hideaki;Miyamoto, Hiroshi
目的：吸入性肺炎的发病率和死亡率被认为是一个主要的老年健康问题。大多数细菌性肺炎病例是在致病菌定植或在咽部重复感染后开始的，然后是咽部内容物的吸入。最近的一项研究表明，细菌通常会导致呼吸道感染，在依赖他人的老年人的假牙上定居。这表明假牙菌斑可能作为潜在呼吸道病原体的储存库，以促进在咽上的定植。本研究的目的是确定义齿和咽菌群之间可能的相关性。研究设计：对50例老年人义齿和咽部细菌菌群进行检测，并通过培养鉴定微生物。采用Kappa法对义齿菌斑细菌种类与咽菌群的一致性进行了研究。结果：受试者义齿与咽黏膜上的微生物种类吻合率为68.5%。假牙和咽部的细菌种类的一致性也很高。结论：义齿应被视为咽部定植组织的重要储存库，控制义齿菌斑对预防吸入性肺炎的重要性再怎么强调也不为过。
OBJECTIVES: The morbidity and mortality of the dependent elderly that result from aspiration pneumonia are recognized as a major geriatric health problem. Most cases of bacterial pneumonia are initiated following colonization or superinfection of the pharynx by pathogenic bacteria, followed by aspiration of pharyngeal contents. A recent study revealed that bacteria, that commonly cause respiratory infection, colonized the dentures of dependent elderly. This suggests that denture plaque may function as a reservoir of potential respiratory pathogens to facilitate colonization on the pharynx. The purpose of this study was to determine the possible correlation between denture and pharyngeal microflora.STUDY DESIGN: The denture and pharyngeal bacterial flora of 50 dependent elderly were examined, and the microorganisms identified by culturing. The agreement between the bacterial species in denture plaque and pharyngeal microflora was investigated using the Kappa method.RESULTS: The microorganism species on the dentures and pharyngeal mucosa of the subjects had an agreement rate of 68.5%. The agreement rate for each of the bacterial species of the dentures and pharynx was also demonstrated to be high.CONCLUSIONS: Dentures should be considered an important reservoir of organisations which could colonise the pharynx, and the importance of controlling denture plaque for the prevention of aspiration pneumonia cannot be overemphasized.