Intense electrochemiluminescence from an organic microcrystal accelerated H2O2-free luminol system for microRNA detection.
Intense electrochemiluminescence from an organic microcrystal accelerated H2O2-free luminol system for microRNA detection.
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DOI：
10.1039/d0cc02207a
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发表时间：
2020-07
影响因子：
4.9
通讯作者：
Li Wang;Ming-Hui Jiang;Y. Chai;R. Yuan;Ying Zhuo
中科院分区：
文献类型：
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作者：
Li Wang;Ming-Hui Jiang;Y. Chai;R. Yuan;Ying Zhuo
A kind of organic microcrystal, 9,10-diphenylanthracene microcrystals (DPA MCs), was developed as a novel electrochemiluminescence (ECL) coreactant accelerator to efficiently catalyze dissolved O2 for more reactive oxygen species (ROSs) generation, achieving intense ECL for a H2O2-free luminol system. Moreover, based on this ternary ECL system, a signal "off-on" ECL biosensor for microRNA-21 (miRNA-21) detection was constructed combining a sensitive target recycling amplification strategy and an enzyme-mediated recycling strand displacement reaction (RSDR).
