Polyamine pools in HIV-infected cells.

Polyamine pools in HIV-infected cells.
复制标题

HIV感染细胞中的多胺库。

DOI:
10.1097/00042560-199802010-00001
复制
发表时间:
1998
期刊:
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association
影响因子:
--
通讯作者:
Secrist3rd,JA
Secrist3rd,JA
中科院分区:
--
文献类型:
--
作者:
White,EL;Rose,LM;Allan,PW;BuckheitJr,RW;Shannon,WM;Secrist3rd,JA

文献摘要

参考文献

被引文献

相似文献

: The polyamines putrescine, spermine, and spermidine, present in all living cells, have been implicated in the replication of some herpesviruses and retroviruses, and elevated levels of these polyamines have been found in the lymphocytes of patients infected with HIV-1. We have examined the effect of HIV-1 infection on polyamine pools in cell culture. HIV-1 did not significantly affect the polyamine pools in CEM cells. Consistent with this observation, inhibitors of the two key enzymes of this pathway, ornithine decarboxylase and S-adenosylmethionine decarboxylase, did not prevent viral-induced cytopathic effects (CPE) in this cell line. Our results indicate that inhibitors of this pathway will not be therapeutically useful in the treatment of AIDS.
腺苷甲硫氨酸脱羧酶抑制剂——缺乏对抗 HIV 细胞病变作用的活性。
DOI: --
发表时间: 1990
期刊: Chemotherapy
影响因子: 3.3
作者:
H. Elo
通讯作者: H. Elo
人巨细胞病毒感染诱导的 S-腺苷甲硫氨酸脱羧酶的表征。
DOI: 10.1016/0168-1702(94)90008-6
发表时间: 1994
期刊: Virus research
影响因子: 5
作者:
White,EL;Arnett,G;Secrist3rd,JA;Shannon,WM
通讯作者: Shannon,WM
通过多胺或蛋氨酸类似物干扰多胺生物合成和/或功能作为潜在的抗癌化疗策略。
DOI: --
发表时间: 1986
影响因子: 2
作者:
Porter,CW;Sufrin,JR
通讯作者: Sufrin,JR
[23] 鸟氨酸脱羧酶(小鼠肾)
DOI: --
发表时间: 1983
期刊:
影响因子: --
作者:
J. Seely;A. Pegg
通讯作者: A. Pegg
1-Aminooxy-3-aminopropane,一种新型有效的多胺生物合成抑制剂,可抑制鸟氨酸脱羧酶、腺苷甲硫氨酸脱羧酶和亚精胺合成酶。
DOI: --
发表时间: 1985
期刊: Biochemical and Biophysical Research Communications - BBRC
影响因子: --
作者:
R. Khomutov;T. Hyvönen;Eija Karvonen;L. Kauppinen;T. Paalanen;L. Paulin;T. Eloranta;R. Pajula;Leif C. Andersson;H. Pösö
通讯作者: H. Pösö