Integrated memory for object, place, and context in rats: A possible model of episodic-like memory?
Integrated memory for object, place, and context in rats: A possible model of episodic-like memory?
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DOI：
10.1523/jneurosci.2975-03.2004
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发表时间：
2004-02-25
影响因子：
5.3
通讯作者：
Norman, G
中科院分区：
文献类型：
--
作者：
Eacott, MJ;Norman, G
我们报道了一项关于一个物体的记忆、它的空间位置以及它出现在老鼠身上的背景的调查。提出了一种基于自发识别范式的新任务，该任务需要对这三个方面进行记忆。这项任务很容易由完整的大鼠以长达1小时的延迟完成。然而，穹隆被切断，任务的执行受到严重和选择性的干扰。执行这项任务的能力与动物的情景记忆模型有关，我们认为这项任务为大鼠提供了一种简单而有用的情景记忆动物模型。
We report an investigation into memory for an object, its spatial location, and the context in which it appeared in rats. A novel task based on the spontaneous recognition paradigm is presented that requires memory for these three aspects. This task is performed easily by intact rats at delays of up to 1 hr. However, performance of the task is severely and selectively disrupted by transection of the fornix. Ability to perform this task is discussed in relation to models of episodic memory in animals, and we suggest that this task provides a simple and useful animal model of episodic memory for use with rats.