SUPEROXIDE-DISMUTASE IN SOME OBLIGATELY ANAEROBIC BACTERIA
SUPEROXIDE-DISMUTASE IN SOME OBLIGATELY ANAEROBIC BACTERIA
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DOI：
10.1016/0014-5793(75)90058-7
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发表时间：
1975-01-01
期刊：
影响因子：
3.5
通讯作者：
MORRIS, JG
中科院分区：
文献类型：
--
作者：
HEWITT, J;MORRIS, JG
需氧和兼性厌氧生物体拥有超氧化物歧化酶，可对氧毒性提供实质性保护 [1, 2]。据报道，这种酶不存在于专性厌氧细菌中 [3]，即对 0.2 个大气压或更低的氧气表现出敏感性的物种 [11。因此，专性厌氧菌和兼性厌氧菌之间的区别（以前是在耐氧谱上绘制的一条有点武断的线）似乎可以用生化术语更令人满意地定义，即：专性厌氧菌缺乏超氧化物歧化酶，兼性（耐氧）厌氧菌含有这种酶。在本次通讯中，我们报告称，拥有超氧化物歧化酶的生物体并不局限于能够在空气中生长的生物体。我们发现超氧化物歧化酶具有中等高的比活性
Substantial protection against oxygen toxicity is afforded to aerobic and facultatively anaerobic organisms by their possession of superoxide dismutase [1, 2]. This enzyme was reportedly not present in obligately anaerobic bacteria [3], ie species which exhibit sensitivity to oxygen at 0.2 atm or less [11. Thus it appeared that the distinction between the obligate and facultative anaerobe, formerly a somewhat arbitrary line drawn on a spectrum of aerotolerance, could be more satisfactorily defined in biochemical terms, viz.: the obligate anaerobe is devoid of superoxide dismutase, the facultative (aerotolerant) anaerobe contains this enzyme. In this communication we report that possession of superoxide dismutase is not restricted to organisms capable of growth in air. We have found superoxide dismutase in moderately high specific activity in