Local field potentials allow accurate decoding of muscle activity
Local field potentials allow accurate decoding of muscle activity
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DOI：
10.1152/jn.00832.2011
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发表时间：
2012-07-01
影响因子：
2.5
通讯作者：
Slutzky, Marc W.
中科院分区：
文献类型：
--
作者：
Flint, Robert D.;Ethier, Christian;Slutzky, Marc W.
Flint RD，Bohler C，Oby ER，米勒LE，Slutzky MW.局部场电位可以准确解码肌肉活动。J Neurophysiol 108：18-24，2012.首次发表于2012年4月11日; doi：10.1152/jn.00832.2011.-初级运动皮层的局部场电位（LFPs）包含了关于到达目标位置和上肢运动学的重要信息。一些证据表明，它们可能是比动作电位（尖峰）更强大，更持久的信号。在这里，我们评估LFP是否也可以用于解码上肢肌肉活动，一个复杂的运动相关信号。我们记录肌电图从近端和远端上肢肌肉从猴子执行各种伸手抓和等长腕力任务。我们表明，LFPs可以用来解码活动从近端和远端肌肉的性能媲美的尖峰。因此，运动皮层LFP包括更多方面的运动比以前已经证明的信息。这提供了进一步的证据，表明LFP可以为神经假体提供高度信息化，持久的信号源。
Flint RD, Ethier C, Oby ER, Miller LE, Slutzky MW. Local field potentials allow accurate decoding of muscle activity. J Neurophysiol 108: 18-24, 2012. First published April 11, 2012; doi:10.1152/jn.00832.2011.-Local field potentials (LFPs) in primary motor cortex include significant information about reach target location and upper limb movement kinematics. Some evidence suggests that they may be a more robust, longer-lasting signal than action potentials (spikes). Here we assess whether LFPs can also be used to decode upper limb muscle activity, a complex movement-related signal. We record electromyograms from both proximal and distal upper limb muscles from monkeys performing a variety of reach-to-grasp and isometric wrist force tasks. We show that LFPs can be used to decode activity from both proximal and distal muscles with performance rivaling that of spikes. Thus, motor cortical LFPs include information about more aspects of movement than has been previously demonstrated. This provides further evidence suggesting that LFPs could provide a highly informative, long-lasting signal source for neural prostheses.